Literature DB >> 17547410

Type-2 isopentenyl diphosphate isomerase. Mechanistic studies with cyclopropyl and epoxy analogues.

Jonathan B Johnston1, Joel R Walker, Steven C Rothman, C Dale Poulter.   

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Year:  2007        PMID: 17547410      PMCID: PMC2494526          DOI: 10.1021/ja072501r

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


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  16 in total

Review 1.  Flavoenzymes that catalyse reactions with no net redox change.

Authors:  Stephen Bornemann
Journal:  Nat Prod Rep       Date:  2002-12       Impact factor: 13.423

2.  Inhibition of type 2 isopentenyl diphosphate isomerase from Methanocaldococcus jannaschii by a mechanism-based inhibitor of type 1 isopentenyl diphosphate isomerase.

Authors:  Takeshi Hoshino; Hideyuki Tamegai; Katsumi Kakinuma; Tadashi Eguchi
Journal:  Bioorg Med Chem       Date:  2006-06-21       Impact factor: 3.641

3.  Escherichia coli type I isopentenyl diphosphate isomerase: structural and catalytic roles for divalent metals.

Authors:  Sungwon Lee; C Dale Poulter
Journal:  J Am Chem Soc       Date:  2006-09-06       Impact factor: 15.419

Review 4.  Diversity of the biosynthesis of the isoprene units.

Authors:  Tomohisa Kuzuyama; Haruo Seto
Journal:  Nat Prod Rep       Date:  2003-04       Impact factor: 13.423

5.  Catalytic mechanism of type 2 isopentenyl diphosphate:dimethylallyl diphosphate isomerase: verification of a redox role of the flavin cofactor in a reaction with no net redox change.

Authors:  Hisashi Hemmi; Yosuke Ikeda; Satoshi Yamashita; Toru Nakayama; Tokuzo Nishino
Journal:  Biochem Biophys Res Commun       Date:  2004-09-24       Impact factor: 3.575

6.  Biochemical characterization of Bacillus subtilis type II isopentenyl diphosphate isomerase, and phylogenetic distribution of isoprenoid biosynthesis pathways.

Authors:  Ralf Laupitz; Stefan Hecht; Sabine Amslinger; Ferdinand Zepeck; Johannes Kaiser; Gerald Richter; Nicholas Schramek; Stefan Steinbacher; Robert Huber; Duilio Arigoni; Adelbert Bacher; Wolfgang Eisenreich; Felix Rohdich
Journal:  Eur J Biochem       Date:  2004-07

7.  Zinc is an essential cofactor for type I isopentenyl diphosphate:dimethylallyl diphosphate isomerase.

Authors:  Christina N Carrigan; C Dale Poulter
Journal:  J Am Chem Soc       Date:  2003-07-30       Impact factor: 15.419

8.  Kinetic and spectroscopic characterization of type II isopentenyl diphosphate isomerase from Thermus thermophilus: evidence for formation of substrate-induced flavin species.

Authors:  Steven C Rothman; Travis R Helm; C Dale Poulter
Journal:  Biochemistry       Date:  2007-04-12       Impact factor: 3.162

9.  Crystal structure of the type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase from Bacillus subtilis.

Authors:  Stefan Steinbacher; Johannes Kaiser; Stefan Gerhardt; Wolfgang Eisenreich; Robert Huber; Adelbert Bacher; Felix Rohdich
Journal:  J Mol Biol       Date:  2003-06-20       Impact factor: 5.469

10.  An unusual isopentenyl diphosphate isomerase found in the mevalonate pathway gene cluster from Streptomyces sp. strain CL190.

Authors:  K Kaneda; T Kuzuyama; M Takagi; Y Hayakawa; H Seto
Journal:  Proc Natl Acad Sci U S A       Date:  2001-01-23       Impact factor: 11.205

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  13 in total

1.  New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase.

Authors:  Hideaki Unno; Satoshi Yamashita; Yosuke Ikeda; Shin-Ya Sekiguchi; Norie Yoshida; Tohru Yoshimura; Masami Kusunoki; Toru Nakayama; Tokuzo Nishino; Hisashi Hemmi
Journal:  J Biol Chem       Date:  2009-01-21       Impact factor: 5.157

Review 2.  Mechanistic aspects of carotenoid biosynthesis.

Authors:  Alexander R Moise; Salim Al-Babili; Eleanore T Wurtzel
Journal:  Chem Rev       Date:  2013-10-31       Impact factor: 60.622

3.  Linear free energy relationships demonstrate a catalytic role for the flavin mononucleotide coenzyme of the type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase.

Authors:  Christopher J Thibodeaux; Wei-chen Chang; Hung-wen Liu
Journal:  J Am Chem Soc       Date:  2010-07-28       Impact factor: 15.419

4.  Inhibition Studies on Enzymes Involved in Isoprenoid Biosynthesis: Focus on Two Potential Drug Targets: DXR and IDI-2 Enzymes.

Authors:  Jérôme de Ruyck; Johan Wouters; C Dale Poulter
Journal:  Curr Enzym Inhib       Date:  2011-07

5.  Type-2 isopentenyl diphosphate isomerase: evidence for a stepwise mechanism.

Authors:  Nicole A Heaps; C Dale Poulter
Journal:  J Am Chem Soc       Date:  2011-11-09       Impact factor: 15.419

6.  Type II isopentenyl diphosphate isomerase: probing the mechanism with alkyne/allene diphosphate substrate analogues.

Authors:  Nagendra K Sharma; Jian-Jung Pan; C Dale Poulter
Journal:  Biochemistry       Date:  2010-07-27       Impact factor: 3.162

7.  Covalent modification of reduced flavin mononucleotide in type-2 isopentenyl diphosphate isomerase by active-site-directed inhibitors.

Authors:  Takuya Nagai; Hideaki Unno; Matthew Walter Janczak; Tohru Yoshimura; C Dale Poulter; Hisashi Hemmi
Journal:  Proc Natl Acad Sci U S A       Date:  2011-12-07       Impact factor: 11.205

Review 8.  Methylerythritol phosphate pathway of isoprenoid biosynthesis.

Authors:  Lishan Zhao; Wei-chen Chang; Youli Xiao; Hung-wen Liu; Pinghua Liu
Journal:  Annu Rev Biochem       Date:  2013       Impact factor: 23.643

9.  Crystal structure of type 2 isopentenyl diphosphate isomerase from Thermus thermophilus in complex with inorganic pyrophosphate.

Authors:  Jérôme de Ruyck; Jenny Pouyez; Steven C Rothman; Dale Poulter; Johan Wouters
Journal:  Biochemistry       Date:  2008-08-12       Impact factor: 3.162

10.  Evidence for the involvement of acid/base chemistry in the reaction catalyzed by the type II isopentenyl diphosphate/dimethylallyl diphosphate isomerase from Staphylococcus aureus.

Authors:  Christopher J Thibodeaux; Steven O Mansoorabadi; William Kittleman; Wei-chen Chang; Hung-wen Liu
Journal:  Biochemistry       Date:  2008-01-30       Impact factor: 3.162

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