Literature DB >> 17541530

[Gene-environment interactions in the pathogenesis and prevention of type 2 diabetes mellitus].

A Fritsche1, C Thamer, N Stefan, H U Häring.   

Abstract

Type 2 diabetes mellitus is a chronic progressive disease characterized by impaired insulin secretion of the beta cell and impaired insulin sensitivity of different tissues. The incidence of type 2 diabetes mellitus is increasing worldwide, and the disease has reached epidemic proportions. Lifestyle intervention programs are able to delay or possibly prevent the manifestation of type 2 diabetes mellitus. This review summarizes the genetic and environmental factors which influence the risk for type 2 diabetes and their interactions, and determine the success of prevention programs.

Entities:  

Mesh：

Year:  2007        PMID： 17541530     DOI： 10.1007/s00108-007-1874-1

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN： 0020-9554            Impact factor:   0.743


  29 in total

1.  The Indian Diabetes Prevention Programme shows that lifestyle modification and metformin prevent type 2 diabetes in Asian Indian subjects with impaired glucose tolerance (IDPP-1).

Authors:  A Ramachandran; C Snehalatha; S Mary; B Mukesh; A D Bhaskar; V Vijay
Journal:  Diabetologia       Date:  2006-01-04       Impact factor: 10.122

2.  Predictors of and longitudinal changes in insulin sensitivity and secretion preceding onset of type 2 diabetes.

Authors:  Valeriya Lyssenko; Peter Almgren; Dragi Anevski; Roland Perfekt; Kaj Lahti; Michael Nissén; Bo Isomaa; Björn Forsen; Nils Homström; Carola Saloranta; Marja-Riitta Taskinen; Leif Groop; Tiinamaija Tuomi
Journal:  Diabetes       Date:  2005-01       Impact factor: 9.461

3.  Physical activity in the prevention of type 2 diabetes: the Finnish diabetes prevention study.

Authors:  David E Laaksonen; Jaana Lindström; Timo A Lakka; Johan G Eriksson; Leo Niskanen; Katja Wikström; Sirkka Aunola; Sirkka Keinänen-Kiukaanniemi; Mauri Laakso; Timo T Valle; Pirjo Ilanne-Parikka; Anne Louheranta; Helena Hämäläinen; Merja Rastas; Virpi Salminen; Zygimantas Cepaitis; Martti Hakumäki; Hannu Kaikkonen; Pirjo Härkönen; Jouko Sundvall; Jaakko Tuomilehto; Matti Uusitupa
Journal:  Diabetes       Date:  2005-01       Impact factor: 9.461

4.  Type 2 diabetes-associated missense polymorphisms KCNJ11 E23K and ABCC8 A1369S influence progression to diabetes and response to interventions in the Diabetes Prevention Program.

Authors:  Jose C Florez; Kathleen A Jablonski; Steven E Kahn; Paul W Franks; Dana Dabelea; Richard F Hamman; William C Knowler; David M Nathan; David Altshuler
Journal:  Diabetes       Date:  2007-02       Impact factor: 9.461

5.  Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes.

Authors:  Struan F A Grant; Gudmar Thorleifsson; Inga Reynisdottir; Rafn Benediktsson; Andrei Manolescu; Jesus Sainz; Agnar Helgason; Hreinn Stefansson; Valur Emilsson; Anna Helgadottir; Unnur Styrkarsdottir; Kristinn P Magnusson; G Bragi Walters; Ebba Palsdottir; Thorbjorg Jonsdottir; Thorunn Gudmundsdottir; Arnaldur Gylfason; Jona Saemundsdottir; Robert L Wilensky; Muredach P Reilly; Daniel J Rader; Yu Bagger; Claus Christiansen; Vilmundur Gudnason; Gunnar Sigurdsson; Unnur Thorsteinsdottir; Jeffrey R Gulcher; Augustine Kong; Kari Stefansson
Journal:  Nat Genet       Date:  2006-01-15       Impact factor: 38.330

6.  Role of insulin secretion and sensitivity in the evolution of type 2 diabetes in the diabetes prevention program: effects of lifestyle intervention and metformin.

Authors:  Abbas E Kitabchi; Marinella Temprosa; William C Knowler; Steven E Kahn; Sarah E Fowler; Steven M Haffner; Reuben Andres; Christopher Saudek; Sharon L Edelstein; Richard Arakaki; Mary Beth Murphy; Harry Shamoon
Journal:  Diabetes       Date:  2005-08       Impact factor: 9.461

7.  TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program.

Authors:  Jose C Florez; Kathleen A Jablonski; Nick Bayley; Toni I Pollin; Paul I W de Bakker; Alan R Shuldiner; William C Knowler; David M Nathan; David Altshuler
Journal:  N Engl J Med       Date:  2006-07-20       Impact factor: 91.245

8.  Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study.

Authors:  X R Pan; G W Li; Y H Hu; J X Wang; W Y Yang; Z X An; Z X Hu; J Lin; J Z Xiao; H B Cao; P A Liu; X G Jiang; Y Y Jiang; J P Wang; H Zheng; H Zhang; P H Bennett; B V Howard
Journal:  Diabetes Care       Date:  1997-04       Impact factor: 19.112

9.  An accurate risk score based on anthropometric, dietary, and lifestyle factors to predict the development of type 2 diabetes.

Authors:  Matthias B Schulze; Kurt Hoffmann; Heiner Boeing; Jakob Linseisen; Sabine Rohrmann; Matthias Möhlig; Andreas F H Pfeiffer; Joachim Spranger; Claus Thamer; Hans-Ulrich Häring; Andreas Fritsche; Hans-Georg Joost
Journal:  Diabetes Care       Date:  2007-03       Impact factor: 19.112

10.  High visceral fat mass and high liver fat are associated with resistance to lifestyle intervention.

Authors:  Claus Thamer; Juergen Machann; Norbert Stefan; Michael Haap; Silke Schäfer; Sonja Brenner; Konstantin Kantartzis; Claus Claussen; Fritz Schick; Hans Haring; Andreas Fritsche
Journal:  Obesity (Silver Spring)       Date:  2007-02       Impact factor: 5.002
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