Literature DB >> 17541193

Steroidal alkaloids from Holarrhena antidysenterica (L.) WALL.

Neeraj Kumar1, Bikram Singh, Pamita Bhandari, Ajai Prakash Gupta, Vijay Kumar Kaul.   

Abstract

Chemical investigations on the stem bark of Holarrhena antidysenterica resulted in the isolation of a new steroidal alkaloid designated as holadysenterine (1), together with three known steroidal alkaloids, conessine (2), isoconessimine (3) and kurchessine (4). Their structures were elucidated on the basis of 1D- and 2D-NMR techniques and high-resolution mass spectrometry.

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Year:  2007        PMID： 17541193     DOI： 10.1248/cpb.55.912

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  10 in total

1.  In vitro elicitation, isolation, and characterization of conessine biomolecule from Holarrhena antidysenterica (L.) Wall. callus and its larvicidal activity against malaria vector, Anopheles stephensi Liston.

Authors:  Dinesh Kumar; Gaurav Kumar; Ram Das; Ravindra Kumar; Veena Agrawal
Journal:  Environ Sci Pollut Res Int       Date:  2017-12-20       Impact factor: 4.223

2.  Escaping mechanisms of ESKAPE pathogens from antibiotics and their targeting by natural compounds.

Authors:  Ragi Jadimurthy; Shilpa Borehalli Mayegowda; S Chandra Nayak; Chakrabhavi Dhananjaya Mohan; Kanchugarakoppal S Rangappa
Journal:  Biotechnol Rep (Amst)       Date:  2022-04-04

Review 3.  Chemistry and bioactivities of natural steroidal alkaloids.

Authors:  Mei-Ling Xiang; Bin-Yuan Hu; Zi-Heng Qi; Xiao-Na Wang; Tian-Zhen Xie; Zhao-Jie Wang; Dan-Yu Ma; Qi Zeng; Xiao-Dong Luo
Journal:  Nat Prod Bioprospect       Date:  2022-06-15

4.  Conessine as a novel inhibitor of multidrug efflux pump systems in Pseudomonas aeruginosa.

Authors:  Thanyaluck Siriyong; Potjanee Srimanote; Sasitorn Chusri; Boon-Ek Yingyongnarongkul; Channarong Suaisom; Varomyalin Tipmanee; Supayang Piyawan Voravuthikunchai
Journal:  BMC Complement Altern Med       Date:  2017-08-14       Impact factor: 3.659

Review 5.  Review on plant antimicrobials: a mechanistic viewpoint.

Authors:  Bahman Khameneh; Milad Iranshahy; Vahid Soheili; Bibi Sedigheh Fazly Bazzaz
Journal:  Antimicrob Resist Infect Control       Date:  2019-07-16       Impact factor: 4.887

6.  In vivo and in silico evaluation of antinociceptive activities of seed extract from the Holarrhena antidysenterica plant.

Authors:  Md Mahbubur Rahman Bhuiyan; N M Mahmudul Alam Bhuiya; Md Nazmul Hasan; Ummey Jannatun Nahar
Journal:  Heliyon       Date:  2020-05-13

7.  Anti-malarial property of steroidal alkaloid conessine isolated from the bark of Holarrhena antidysenterica.

Authors:  Virendra K Dua; Gaurav Verma; Bikram Singh; Aswathy Rajan; Upma Bagai; Dau Dayal Agarwal; N C Gupta; Sandeep Kumar; Ayushi Rastogi
Journal:  Malar J       Date:  2013-06-10       Impact factor: 2.979

8.  In vivo antimalarial activity of extracts of Tanzanian medicinal plants used for the treatment of malaria.

Authors:  Ramadhani S O Nondo; Paul Erasto; Mainen J Moshi; Abdallah Zacharia; Pax J Masimba; Abdul W Kidukuli
Journal:  J Adv Pharm Technol Res       Date:  2016 Apr-Jun

9.  Steroidal alkaloids and conessine from the medicinal plant Holarrhena antidysenterica restore antibiotic efficacy in a Galleria mellonella model of multidrug-resistant Pseudomonas aeruginosa infection.

Authors:  Thanyaluck Siriyong; Supayang Piyawan Voravuthikunchai; Peter John Coote
Journal:  BMC Complement Altern Med       Date:  2018-10-19       Impact factor: 3.659

Review 10.  Metabolic Diversity and Therapeutic Potential of Holarrhena pubescens: An Important Ethnomedicinal Plant.

Authors:  Kulsoom Zahara; Sujogya Kumar Panda; Shasank Sekhar Swain; Walter Luyten
Journal:  Biomolecules       Date:  2020-09-18
  10 in total

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