Literature DB >> 17539893

TRPV1 in colitis: is it a good or a bad receptor?--a viewpoint.

M Storr.   

Abstract

The role of the transient receptor potential vanilloid-1 (TRPV1) has been repeatedly investigated in animal models of inflammation. The present issue of Neurogastroenterology and Motility includes another report on this issue and, not unexpectedly, many questions on the precise role of TRPV1 receptors in inflammation remain unanswered. This Editorial Viewpoint discusses the present knowledge on TRPV1 receptor involvement in intestinal inflammation and discusses the question whether the TRPV1 has to be regarded as the good or the bad receptor in this context. Since TRPV1 activation turns out being a valuable approach, translation of this knowledge to human disease is highly recommended.

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Year:  2007        PMID： 17539893     DOI： 10.1111/j.1365-2982.2007.00946.x

Source DB:  PubMed          Journal:  Neurogastroenterol Motil        ISSN： 1350-1925            Impact factor:   3.598


  11 in total

Review 1.  Ion channel remodeling in gastrointestinal inflammation.

Authors:  H I Akbarali; E G Hawkins; G R Ross; M Kang
Journal:  Neurogastroenterol Motil       Date:  2010-07-05       Impact factor: 3.598

Review 2.  Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system.

Authors:  Peter Holzer
Journal:  Pharmacol Ther       Date:  2011-03-21       Impact factor: 12.310

Review 3.  TRPV1: a new target for treatment of visceral pain in IBS?

Authors:  Peter Holzer
Journal:  Gut       Date:  2008-07       Impact factor: 23.059

Review 4.  Sensory TRP channels: the key transducers of nociception and pain.

Authors:  Aaron D Mickle; Andrew J Shepherd; Durga P Mohapatra
Journal:  Prog Mol Biol Transl Sci       Date:  2015-02-12       Impact factor: 3.622

5.  Palmitoylethanolamide regulates development of intestinal radiation injury in a mast cell-dependent manner.

Authors:  Junru Wang; Junying Zheng; Ashwini Kulkarni; Wen Wang; Sarita Garg; Paul L Prather; Martin Hauer-Jensen
Journal:  Dig Dis Sci       Date:  2014-05-22       Impact factor: 3.199

6.  The role of transient receptor potential vanilloid 1 (TRPV1) receptors in dextran sulfate-induced colitis in mice.

Authors:  Istvan Szitter; Gabor Pozsgai; Katalin Sandor; Krisztian Elekes; Agnes Kemeny; Aniko Perkecz; Janos Szolcsanyi; Zsuzsanna Helyes; Erika Pinter
Journal:  J Mol Neurosci       Date:  2010-04-22       Impact factor: 3.444

7.  Targeting endocannabinoid degradation protects against experimental colitis in mice: involvement of CB1 and CB2 receptors.

Authors:  Martin A Storr; Catherine M Keenan; Dominik Emmerdinger; Hong Zhang; Birol Yüce; Andrei Sibaev; Federico Massa; Nancy E Buckley; Beat Lutz; Burkhard Göke; Stephan Brand; Kamala D Patel; Keith A Sharkey
Journal:  J Mol Med (Berl)       Date:  2008-05-21       Impact factor: 4.599

Review 8.  The pharmacological challenge to tame the transient receptor potential vanilloid-1 (TRPV1) nocisensor.

Authors:  P Holzer
Journal:  Br J Pharmacol       Date:  2008-09-22       Impact factor: 8.739

Review 9.  Nociceptive TRP Channels: Sensory Detectors and Transducers in Multiple Pain Pathologies.

Authors:  Aaron D Mickle; Andrew J Shepherd; Durga P Mohapatra
Journal:  Pharmaceuticals (Basel)       Date:  2016-11-14

10.  Lack of transient receptor potential vanilloid 1 channel modulates the development of neurogenic bladder dysfunction induced by cross-sensitization in afferent pathways.

Authors:  Qi Lei; Xiao-Qing Pan; Antonio N Villamor; Tirsit S Asfaw; Shaohua Chang; Steven A Zderic; Anna P Malykhina
Journal:  J Neuroinflammation       Date:  2013-01-11       Impact factor: 8.322
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