Literature DB >> 25744671

Sensory TRP channels: the key transducers of nociception and pain.

Aaron D Mickle1, Andrew J Shepherd1, Durga P Mohapatra2.   

Abstract

Peripheral detection of nociceptive and painful stimuli by sensory neurons involves a complex repertoire of molecular detectors and/or transducers on distinct subsets of nerve fibers. The majority of such molecular detectors/transducers belong to the transient receptor potential (TRP) family of cation channels, which comprise both specific receptors for distinct nociceptive stimuli, as well as for multiple stimuli. This chapter discusses the classification, distribution, and functional properties of individual TRP channel types that have been implicated in various nociceptive and/or painful conditions.
© 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Nociception; Pain; TRP channel; TRPA1; TRPM3; TRPM8; TRPV1; TRPV2; TRPV3; TRPV4

Mesh：

Substances：

Year:  2015        PMID： 25744671      PMCID： PMC5903472          DOI： 10.1016/bs.pmbts.2015.01.002

Source DB:  PubMed          Journal:  Prog Mol Biol Transl Sci        ISSN： 1877-1173            Impact factor:   3.622


  268 in total

1.  General anesthetics activate a nociceptive ion channel to enhance pain and inflammation.

Authors:  José A Matta; Paul M Cornett; Rosa L Miyares; Ken Abe; Niaz Sahibzada; Gerard P Ahern
Journal:  Proc Natl Acad Sci U S A       Date:  2008-06-23       Impact factor: 11.205

2.  Evidence for the pathophysiological relevance of TRPA1 receptors in the cardiovascular system in vivo.

Authors:  Gabor Pozsgai; Jennifer V Bodkin; Rabea Graepel; Stuart Bevan; David A Andersson; Susan D Brain
Journal:  Cardiovasc Res       Date:  2010-05-03       Impact factor: 10.787

3.  TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ(9)-tetrahydrocannabiorcol.

Authors:  David A Andersson; Clive Gentry; Lisa Alenmyr; Dan Killander; Simon E Lewis; Anders Andersson; Bernard Bucher; Jean-Luc Galzi; Olov Sterner; Stuart Bevan; Edward D Högestätt; Peter M Zygmunt
Journal:  Nat Commun       Date:  2011-11-22       Impact factor: 14.919

4.  Physiologic and antinociceptive effects of intrathecal resiniferatoxin in a canine bone cancer model.

Authors:  Dorothy Cimino Brown; Michael J Iadarola; Sandra Z Perkowski; Hardam Erin; Frances Shofer; Karai J Laszlo; Zoltan Olah; Andrew J Mannes
Journal:  Anesthesiology       Date:  2005-11       Impact factor: 7.892

5.  Primary alcohols activate human TRPA1 channel in a carbon chain length-dependent manner.

Authors:  Tomoko Komatsu; Kunitoshi Uchida; Fumitaka Fujita; Yiming Zhou; Makoto Tominaga
Journal:  Pflugers Arch       Date:  2012-01-06       Impact factor: 3.657

6.  Modulation of TRPV1 by nonreceptor tyrosine kinase, c-Src kinase.

Authors:  Xiaochun Jin; Nemat Morsy; John Winston; Pankaj J Pasricha; Kennon Garrett; Hamid I Akbarali
Journal:  Am J Physiol Cell Physiol       Date:  2004-04-14       Impact factor: 4.249

7.  Pharmacology and antitussive efficacy of 4-(3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carboxylic acid (5-trifluoromethyl-pyridin-2-yl)-amide (JNJ17203212), a transient receptor potential vanilloid 1 antagonist in guinea pigs.

Authors:  Anindya Bhattacharya; Brian P Scott; Nadia Nasser; Hong Ao; Michael P Maher; Adrienne E Dubin; Devin M Swanson; Nigel P Shankley; Alan D Wickenden; Sandra R Chaplan
Journal:  J Pharmacol Exp Ther       Date:  2007-08-09       Impact factor: 4.030

8.  Pharmacology of modality-specific transient receptor potential vanilloid-1 antagonists that do not alter body temperature.

Authors:  Regina M Reilly; Heath A McDonald; Pamela S Puttfarcken; Shailen K Joshi; LaGeisha Lewis; Madhavi Pai; Pamela H Franklin; Jason A Segreti; Torben R Neelands; Ping Han; Jun Chen; Patrick W Mantyh; Joseph R Ghilardi; Teresa M Turner; Eric A Voight; Jerome F Daanen; Robert G Schmidt; Arthur Gomtsyan; Michael E Kort; Connie R Faltynek; Philip R Kym
Journal:  J Pharmacol Exp Ther       Date:  2012-05-08       Impact factor: 4.030

9.  Expression of transient receptor potential ankyrin 1 (TRPA1) and its role in insulin release from rat pancreatic beta cells.

Authors:  De-Shou Cao; Linlin Zhong; Tsung-Han Hsieh; Mruvil Abooj; Mahendra Bishnoi; Lauren Hughes; Louis S Premkumar
Journal:  PLoS One       Date:  2012-05-31       Impact factor: 3.240

10.  No requirement of TRPV1 in long-term potentiation or long-term depression in the anterior cingulate cortex.

Authors:  Ming-Gang Liu; Min Zhuo
Journal:  Mol Brain       Date:  2014-04-05       Impact factor: 4.041
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  49 in total

Review 1.  Neuronal transient receptor potential (TRP) channels and noxious sensory detection in sickle cell disease.

Authors:  Katelyn E Sadler; Cheryl L Stucky
Journal:  Neurosci Lett       Date:  2018-11-30       Impact factor: 3.046

Review 2.  Signalling in response to sub-picomolar concentrations of active compounds: Pushing the boundaries of GPCR sensitivity.

Authors:  Srgjan Civciristov; Michelle L Halls
Journal:  Br J Pharmacol       Date:  2019-04-05       Impact factor: 8.739

Review 3.  The function and regulation of acid-sensing ion channels (ASICs) and the epithelial Na(+) channel (ENaC): IUPHAR Review 19.

Authors:  Emilie Boscardin; Omar Alijevic; Edith Hummler; Simona Frateschi; Stephan Kellenberger
Journal:  Br J Pharmacol       Date:  2016-08-10       Impact factor: 8.739

4.  GPR119 Agonist AS1269574 Activates TRPA1 Cation Channels to Stimulate GLP-1 Secretion.

Authors:  Oleg G Chepurny; George G Holz; Michael W Roe; Colin A Leech
Journal:  Mol Endocrinol       Date:  2016-04-15

Review 5.  Role of Oxidized Lipids and TRP Channels in Orofacial Pain and Inflammation.

Authors:  K M Hargreaves; S Ruparel
Journal:  J Dent Res       Date:  2016-06-15       Impact factor: 6.116

6.  Angiotensin II Triggers Peripheral Macrophage-to-Sensory Neuron Redox Crosstalk to Elicit Pain.

Authors:  Andrew J Shepherd; Bryan A Copits; Aaron D Mickle; Páll Karlsson; Suraj Kadunganattil; Simon Haroutounian; Satya M Tadinada; Annette D de Kloet; Manouela V Valtcheva; Lisa A McIlvried; Tayler D Sheahan; Sanjay Jain; Pradipta R Ray; Yuriy M Usachev; Gregory Dussor; Eric G Krause; Theodore J Price; Robert W Gereau; Durga P Mohapatra
Journal:  J Neurosci       Date:  2018-07-05       Impact factor: 6.167

7.  Sites Contributing to TRPA1 Activation by the Anesthetic Propofol Identified by Photoaffinity Labeling.

Authors:  Kellie A Woll; Kenneth A Skinner; Eleonora Gianti; Natarajan V Bhanu; Benjamin A Garcia; Vincenzo Carnevale; Roderic G Eckenhoff; Rachelle Gaudet
Journal:  Biophys J       Date:  2017-09-19       Impact factor: 4.033

Review 8.  Neuropathic Pain: Central vs. Peripheral Mechanisms.

Authors:  Kathleen Meacham; Andrew Shepherd; Durga P Mohapatra; Simon Haroutounian
Journal:  Curr Pain Headache Rep       Date:  2017-06

9.  The Complement System Component C5a Produces Thermal Hyperalgesia via Macrophage-to-Nociceptor Signaling That Requires NGF and TRPV1.

Authors:  Leonid P Shutov; Charles A Warwick; Xiaoyu Shi; Aswini Gnanasekaran; Andrew J Shepherd; Durga P Mohapatra; Trent M Woodruff; J David Clark; Yuriy M Usachev
Journal:  J Neurosci       Date:  2016-05-04       Impact factor: 6.167

10.  Macrophage angiotensin II type 2 receptor triggers neuropathic pain.

Authors:  Andrew J Shepherd; Aaron D Mickle; Judith P Golden; Madison R Mack; Carmen M Halabi; Annette D de Kloet; Vijay K Samineni; Brian S Kim; Eric G Krause; Robert W Gereau; Durga P Mohapatra
Journal:  Proc Natl Acad Sci U S A       Date:  2018-08-06       Impact factor: 11.205
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