Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Insertional mutagenesis to generate lantibiotic resistance in Lactococcus lactis.

Literature DB >> 17526796

Insertional mutagenesis to generate lantibiotic resistance in Lactococcus lactis.

Caitriona M Guinane¹, Paul D Cotter, Elaine M Lawton, Colin Hill, R Paul Ross.

Abstract

While the potential emergence of food spoilage and pathogenic bacteria with resistance to lantibiotics is a concern, the creation of derivatives of starter cultures and adjuncts that can grow in the presence of these antimicrobials may have applications in food fermentations. Here a bank of Lactococcus lactis IL1403 mutants was created and screened, and a number of novel genetic loci involved in lantibiotic resistance were identified.

Entities: Species

Mesh：

Substances：

Year: 2007 PMID： 17526796 PMCID： PMC1932815 DOI： 10.1128/AEM.02351-06

Source DB: PubMed Journal: Appl Environ Microbiol ISSN： 0099-2240 Impact factor: 4.792

29 in total

1. Identification and disruption of lisRK, a genetic locus encoding a two-component signal transduction system involved in stress tolerance and virulence in Listeria monocytogenes.

Authors: P D Cotter; N Emerson; C G Gahan; C Hill
Journal: J Bacteriol Date: 1999-11 Impact factor: 3.490

2. Frequency of bacteriocin resistance development and associated fitness costs in Listeria monocytogenes.

Authors: A Gravesen; A-M Jydegaard Axelsen; J Mendes da Silva; T B Hansen; S Knøchel
Journal: Appl Environ Microbiol Date: 2002-02 Impact factor: 4.792

3. Each peptide of the two-component lantibiotic lacticin 3147 requires a separate modification enzyme for activity.

Authors: Olivia McAuliffe; Colin Hill; R Paul Ross
Journal: Microbiology (Reading) Date: 2000-09 Impact factor: 2.777

4. Insertion-sequence-mediated mutations isolated during adaptation to growth and starvation in Lactococcus lactis.

Authors: J Arjan G M de Visser; Antoon D L Akkermans; Rolf F Hoekstra; Willem M de Vos
Journal: Genetics Date: 2004-11 Impact factor: 4.562

Review 5. Microbial solutions to microbial problems; lactococcal bacteriocins for the control of undesirable biota in food.

Authors: C M Guinane; P D Cotter; C Hill; R P Ross
Journal: J Appl Microbiol Date: 2005 Impact factor: 3.772

Insertional mutagenesis to generate lantibiotic resistance in Lactococcus lactis.

1. Identification and disruption of lisRK, a genetic locus encoding a two-component signal transduction system involved in stress tolerance and virulence in Listeria monocytogenes.

2. Frequency of bacteriocin resistance development and associated fitness costs in Listeria monocytogenes.

3. Each peptide of the two-component lantibiotic lacticin 3147 requires a separate modification enzyme for activity.

4. Insertion-sequence-mediated mutations isolated during adaptation to growth and starvation in Lactococcus lactis.

Review 5. Microbial solutions to microbial problems; lactococcal bacteriocins for the control of undesirable biota in food.

6. Spontaneous resistance in Lactococcus lactis IL1403 to the lantibiotic lacticin 3147.

7. Overproduction of wild-type and bioengineered derivatives of the lantibiotic lacticin 3147.

8. Transcriptome analysis reveals mechanisms by which Lactococcus lactis acquires nisin resistance.

9. Acid-adapted Listeria monocytogenes displays enhanced tolerance against the lantibiotics nisin and lacticin 3147.

10. Bioenergetic mechanism for nisin resistance, induced by the acid tolerance response of Listeria monocytogenes.

1. Glutamate decarboxylase-mediated nisin resistance in Listeria monocytogenes.