OBJECTIVE: To determine the point prevalence, incidence, and remission over a 2-year period of psychosis in adults with intellectual disabilities, and to investigate demographic and clinical factors hypothesised to be associated with psychosis. METHOD: A population-based cohort of adults with intellectual disabilities (n = 1,023) was longitudinally studied. Comprehensive face-to-face mental health assessments to detect psychosis, plus review of family physician, psychiatric, and psychology case notes were undertaken at two time points, 2 years apart. RESULTS: Point prevalence is 2.6% (95% CI = 1.8-3.8%) to 4.4% (95% CI = 3.2-5.8%), dependant upon the diagnostic criteria employed. Two-year incidence is 1.4% (95% CI = 0.6-2.6), and for first episode is 0.5% (95% CI = 0.1-1.3). Compared with the general population, the standardised incidence ratio for first episode psychosis is 10.0 (95% CI = 2.1-29.3). Full remission after 2 years is 14.3%. Visual impairment, previous long-stay hospital residence, smoking, and not having epilepsy were independently associated with psychosis, whereas other factors relevant to the general population were not. CONCLUSIONS: The study of psychosis in persons with intellectual disabilities benefits the population with intellectual disabilities, and advances the understanding of psychosis for the general population. Mental health professionals need adequate knowledge in order to address the high rates of psychosis in this population.
OBJECTIVE: To determine the point prevalence, incidence, and remission over a 2-year period of psychosis in adults with intellectual disabilities, and to investigate demographic and clinical factors hypothesised to be associated with psychosis. METHOD: A population-based cohort of adults with intellectual disabilities (n = 1,023) was longitudinally studied. Comprehensive face-to-face mental health assessments to detect psychosis, plus review of family physician, psychiatric, and psychology case notes were undertaken at two time points, 2 years apart. RESULTS: Point prevalence is 2.6% (95% CI = 1.8-3.8%) to 4.4% (95% CI = 3.2-5.8%), dependant upon the diagnostic criteria employed. Two-year incidence is 1.4% (95% CI = 0.6-2.6), and for first episode is 0.5% (95% CI = 0.1-1.3). Compared with the general population, the standardised incidence ratio for first episode psychosis is 10.0 (95% CI = 2.1-29.3). Full remission after 2 years is 14.3%. Visual impairment, previous long-stay hospital residence, smoking, and not having epilepsy were independently associated with psychosis, whereas other factors relevant to the general population were not. CONCLUSIONS: The study of psychosis in persons with intellectual disabilities benefits the population with intellectual disabilities, and advances the understanding of psychosis for the general population. Mental health professionals need adequate knowledge in order to address the high rates of psychosis in this population.
Authors: H M J van Schrojenstein Lantman-de Valk; M Wullink; M van den Akker; E W A van Heurn-Nijsten; J F M Metsemakers; G J Dinant Journal: J Intellect Disabil Res Date: 2006-01
Authors: Traolach Brugha; Nicola Singleton; Howard Meltzer; Paul Bebbington; Michael Farrell; Rachel Jenkins; Jeremy Coid; Tom Fryers; David Melzer; Glyn Lewis Journal: Am J Psychiatry Date: 2005-04 Impact factor: 18.112
Authors: Louise C Johns; Mary Cannon; Nicola Singleton; Robin M Murray; Michael Farrell; Traolach Brugha; Paul Bebbington; Rachel Jenkins; Howard Meltzer Journal: Br J Psychiatry Date: 2004-10 Impact factor: 9.319
Authors: James B Kirkbride; Paul Fearon; Craig Morgan; Paola Dazzan; Kevin Morgan; Jane Tarrant; Tuhina Lloyd; John Holloway; Gerard Hutchinson; Julian P Leff; Rosemarie M Mallett; Glynn L Harrison; Robin M Murray; Peter B Jones Journal: Arch Gen Psychiatry Date: 2006-03
Authors: Matthias Schützwohl; Andrea Koch; Nadine Koslowski; Bernd Puschner; Elke Voß; Hans Joachim Salize; Andrea Pfennig; Anke Vogel Journal: Soc Psychiatry Psychiatr Epidemiol Date: 2016-03-07 Impact factor: 4.328