Literature DB >> 17502856

Filaggrin's fuller figure: a glimpse into the genetic architecture of atopic dermatitis.

Aileen Sandilands1, Frances J D Smith, Alan D Irvine, W H Irwin McLean.   

Abstract

Prevalent mutations in the FLG gene underlie the common skin disorder ichthyosis vulgaris and are significant risk factors for atopic dermatitis (eczema). The recent publication of a strategy to sequence this difficult gene identifies a spectrum of both prevalent and rare mutations that collectively have a significant impact on susceptibility to atopic disease.

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Year:  2007        PMID： 17502856     DOI： 10.1038/sj.jid.5700876

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN： 0022-202X            Impact factor:   8.551


  38 in total

Review 1.  Basis for the barrier abnormality in atopic dermatitis: outside-inside-outside pathogenic mechanisms.

Authors:  Peter M Elias; Yutaka Hatano; Mary L Williams
Journal:  J Allergy Clin Immunol       Date:  2008-03-07       Impact factor: 10.793

Review 2.  Abnormal skin barrier in the etiopathogenesis of atopic dermatitis.

Authors:  Peter M Elias; Matthias Schmuth
Journal:  Curr Allergy Asthma Rep       Date:  2009-07       Impact factor: 4.806

Review 3.  Lipid abnormalities and lipid-based repair strategies in atopic dermatitis.

Authors:  Peter M Elias
Journal:  Biochim Biophys Acta       Date:  2013-10-12

Review 4.  Animal models of skin disease for drug discovery.

Authors:  Pinar Avci; Magesh Sadasivam; Asheesh Gupta; Wanessa Cma De Melo; Ying-Ying Huang; Rui Yin; Rakkiyappan Chandran; Raj Kumar; Ayodeji Otufowora; Theodore Nyame; Michael R Hamblin
Journal:  Expert Opin Drug Discov       Date:  2013-01-08       Impact factor: 6.098

5.  Skin Diseases in Laboratory Mice: Approaches to Drug Target Identification and Efficacy Screening.

Authors:  John P Sundberg; Kathleen A Silva; Lloyd E King; C Herbert Pratt
Journal:  Methods Mol Biol       Date:  2016

Review 6.  Therapeutic implications of a barrier-based pathogenesis of atopic dermatitis.

Authors:  Peter M Elias; Joan S Wakefield
Journal:  Clin Rev Allergy Immunol       Date:  2011-12       Impact factor: 8.667

7.  Reduced inflammatory threshold indicates skin barrier defect in transglutaminase 3 knockout mice.

Authors:  Peter Bognar; Ilona Nemeth; Balazs Mayer; Dora Haluszka; Norbert Wikonkal; Eszter Ostorhazi; Susan John; Mats Paulsson; Neil Smyth; Maria Pasztoi; Edit I Buzas; Robert Szipocs; Attila Kolonics; Erzsebet Temesvari; Sarolta Karpati
Journal:  J Invest Dermatol       Date:  2013-07-24       Impact factor: 8.551

Review 8.  Mechanisms of abnormal lamellar body secretion and the dysfunctional skin barrier in patients with atopic dermatitis.

Authors:  Peter M Elias; Joan S Wakefield
Journal:  J Allergy Clin Immunol       Date:  2014-08-15       Impact factor: 10.793

9.  Epidermal barrier dysfunction in non-atopic HIV: evidence for an "inside-to-outside" pathogenesis.

Authors:  Roshan Gunathilake; Matthias Schmuth; Tiffany C Scharschmidt; Robert Gruber; Daniela Grabher; Kieron S Leslie; Toby A Maurer; Theodora M Mauro; Peter M Elias
Journal:  J Invest Dermatol       Date:  2009-11-19       Impact factor: 8.551

10.  Epidermal vascular endothelial growth factor production is required for permeability barrier homeostasis, dermal angiogenesis, and the development of epidermal hyperplasia: implications for the pathogenesis of psoriasis.

Authors:  Peter M Elias; Jack Arbiser; Barbara E Brown; Heidemarie Rossiter; Mao-Qiang Man; Francesca Cerimele; Debra Crumrine; Roshan Gunathilake; Eung Ho Choi; Yoshikazu Uchida; Erwin Tschachler; Kenneth R Feingold
Journal:  Am J Pathol       Date:  2008-08-07       Impact factor: 4.307
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