| Literature DB >> 17502237 |
Jeremy Nuttall1, Joseph Romano, Karen Douville, Caroline Galbreath, Annaléne Nel, William Heyward, Mark Mitchnick, Saul Walker, Zeda Rosenberg.
Abstract
Topical microbicides are self-administered products for prevention of HIV transmission, and they present one of the most promising strategies for combating the HIV-AIDS epidemic. The development of microbicides is a long and complicated process, with many hurdles that are unique to this class of product, including challenges in product design, in the conduct and design of clinical trials, and in obtaining licensure of a new class of products intended for use almost exclusively in developing countries. Once they have been registered, there are additional challenges to the marketing and distribution of microbicides. An overview of the types of microbicide currently in development, and a summary of the issues and the approaches being taken to address them, are provided.Entities:
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Year: 2007 PMID： 17502237 DOI： 10.1016/j.idc.2007.01.009
Source DB: PubMed Journal: Infect Dis Clin North Am ISSN： 0891-5520 Impact factor: 5.982