Literature DB >> 17500918

Stretching short biopolymers by fields and forces.

Yuko Hori1, Ashok Prasad, Jané Kondev.   

Abstract

We study the mechanical properties of semiflexible polymers when the contour length of the polymer is comparable to its persistence length. We compute the exact average end-to-end distance and shape of the polymer for different boundary conditions, and show that boundary effects can lead to significant deviations from the well-known long-polymer results. We also consider the case of stretching a uniformly charged biopolymer by an electric field, for which we compute the average extension and the average shape, which is shown to be trumpetlike. Our results also apply to long biopolymers when thermal fluctuations have been smoothed out by a large applied field or force.

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Year:  2007        PMID: 17500918     DOI: 10.1103/PhysRevE.75.041904

Source DB:  PubMed          Journal:  Phys Rev E Stat Nonlin Soft Matter Phys        ISSN: 1539-3755


  2 in total

1.  Elasticity of short DNA molecules: theory and experiment for contour lengths of 0.6-7 microm.

Authors:  Yeonee Seol; Jinyu Li; Philip C Nelson; Thomas T Perkins; M D Betterton
Journal:  Biophys J       Date:  2007-08-31       Impact factor: 4.033

2.  Minimizing pulling geometry errors in atomic force microscope single molecule force spectroscopy.

Authors:  Monica Rivera; Whasil Lee; Changhong Ke; Piotr E Marszalek; Daniel G Cole; Robert L Clark
Journal:  Biophys J       Date:  2008-07-18       Impact factor: 4.033

  2 in total

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