Literature DB >> 17487588

Normal levels of serum IGF-I: determinants and validity of current reference ranges.

G Brabant1, H Wallaschofski.   

Abstract

Insulin like growth factor I (IGF-I) represents the key marker for the evaluation of Growth hormone (GH) status. As a large number of determinants including age, gender, genetic factors, nutrition, and disease states influence IGF-I serum levels, accurate normative data are essential to translate patient data into diagnostic meaning or even use IGF-I levels for adequate monitoring of patients with an over- or under-active GH axis. Even though reference ranges have been developed in large cohorts of healthy subjects, the dependency of these data on a given assay technology argues for assay specific normative data for IGF-I.

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Year:  2007        PMID: 17487588     DOI: 10.1007/s11102-007-0035-9

Source DB:  PubMed          Journal:  Pituitary        ISSN: 1386-341X            Impact factor:   3.599


  39 in total

1.  A polymorphism in the gene for IGF-I: functional properties and risk for type 2 diabetes and myocardial infarction.

Authors:  N Vaessen; P Heutink; J A Janssen; J C Witteman; L Testers; A Hofman; S W Lamberts; B A Oostra; H A Pols; C M van Duijn
Journal:  Diabetes       Date:  2001-03       Impact factor: 9.461

2.  An exonic splicing enhancer in human IGF-I pre-mRNA mediates recognition of alternative exon 5 by the serine-arginine protein splicing factor-2/alternative splicing factor.

Authors:  Philip J Smith; Emma L Spurrell; John Coakley; Charles J Hinds; Richard J M Ross; Adrian R Krainer; Shern L Chew
Journal:  Endocrinology       Date:  2002-01       Impact factor: 4.736

3.  Variability and reliability of single serum IGF-I measurements: impact on determining predictability of risk ratios in disease development.

Authors:  Daniela Milani; John D Carmichael; Joan Welkowitz; Steven Ferris; Richard E Reitz; Ann Danoff; David L Kleinberg
Journal:  J Clin Endocrinol Metab       Date:  2004-05       Impact factor: 5.958

Review 4.  The role of the IGF system in cancer growth and metastasis: overview and recent insights.

Authors:  Amir Abbas Samani; Shoshana Yakar; Derek LeRoith; Pnina Brodt
Journal:  Endocr Rev       Date:  2006-08-24       Impact factor: 19.871

Review 5.  Nutritional regulation of the insulin-like growth factors.

Authors:  J P Thissen; J M Ketelslegers; L E Underwood
Journal:  Endocr Rev       Date:  1994-02       Impact factor: 19.871

6.  Changes in subcutaneous and visceral fat mass during growth hormone replacement therapy in adult men.

Authors:  H de Boer; G J Blok; B Voerman; P Derriks; E van der Veen
Journal:  Int J Obes Relat Metab Disord       Date:  1996-06

7.  Insulin-like growth factor-I is an autocrine regulator of chromogranin A secretion and growth in human neuroendocrine tumor cells.

Authors:  G von Wichert; P M Jehle; A Hoeflich; S Koschnick; H Dralle; E Wolf; B Wiedenmann; B O Boehm; G Adler; T Seufferlein
Journal:  Cancer Res       Date:  2000-08-15       Impact factor: 12.701

Review 8.  Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis.

Authors:  Andrew G Renehan; Marcel Zwahlen; Christoph Minder; Sarah T O'Dwyer; Stephen M Shalet; Matthias Egger
Journal:  Lancet       Date:  2004-04-24       Impact factor: 79.321

9.  Serum IGF-I and IGFBP-3 levels of Turkish children during childhood and adolescence: establishment of reference ranges with emphasis on puberty.

Authors:  Abdullah Bereket; Serap Turan; Anjumanara Omar; Mustafa Berber; Ahmet Ozen; Cengiz Akbenlioglu; Goncagul Haklar
Journal:  Horm Res       Date:  2006-02-03

10.  Low serum insulin-like growth factor I is associated with increased risk of ischemic heart disease: a population-based case-control study.

Authors:  Anders Juul; Thomas Scheike; Michael Davidsen; Jesper Gyllenborg; Torben Jørgensen
Journal:  Circulation       Date:  2002-08-20       Impact factor: 29.690

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  21 in total

1.  Bone density in post-pubertal adolescent survivors of childhood brain tumors.

Authors:  Laurie E Cohen; Joshua H Gordon; Erica Y Popovsky; Nina N Sainath; Henry A Feldman; Mark W Kieran; Catherine M Gordon
Journal:  Pediatr Blood Cancer       Date:  2011-08-29       Impact factor: 3.167

Review 2.  The effects of testosterone and insulin-like growth factor 1 on motor system form and function.

Authors:  Kentaro Oki; Timothy D Law; Anne B Loucks; Brian C Clark
Journal:  Exp Gerontol       Date:  2015-02-11       Impact factor: 4.032

3.  Reference ranges for an automated chemiluminescent assay for serum insulin-like growth factor I (IGF-I) in a large population of healthy adults from Buenos Aires.

Authors:  M Guitelman; F Smithuis; N Garcia Basavilbaso; C Aranda; B Fabre; A Oneto
Journal:  J Endocrinol Invest       Date:  2015-03-05       Impact factor: 4.256

4.  Chronic activity-based therapy does not improve body composition, insulin-like growth factor-I, adiponectin, or myostatin in persons with spinal cord injury.

Authors:  Todd A Astorino; Eric T Harness; Kara A Witzke
Journal:  J Spinal Cord Med       Date:  2014-08-17       Impact factor: 1.985

Review 5.  How useful are serum IGF-I measurements for managing GH replacement therapy in adults and children?

Authors:  Anna Pawlikowska-Haddal; Pinchas Cohen; David M Cook
Journal:  Pituitary       Date:  2012-06       Impact factor: 4.107

6.  Growth hormone-dependent changes in the rat lung proteome during alveorization.

Authors:  J A Beyea; D M Olson; S Harvey
Journal:  Mol Cell Biochem       Date:  2008-11-05       Impact factor: 3.396

7.  Insulin like growth factor-I in acute subarachnoid hemorrhage: a prospective cohort study.

Authors:  Stepani Bendel; Timo Koivisto; Olli-Pekka Ryynänen; Esko Ruokonen; Jarkko Romppanen; Vesa Kiviniemi; Ari Uusaro
Journal:  Crit Care       Date:  2010-04-28       Impact factor: 9.097

8.  Paracrine overexpression of insulin-like growth factor-1 enhances mammary tumorigenesis in vivo.

Authors:  Krisztina Kovács de Ostrovich; Isabel Lambertz; Jennifer K L Colby; Jie Tian; Joyce E Rundhaug; Dennis Johnston; Claudio J Conti; John DiGiovanni; Robin Fuchs-Young
Journal:  Am J Pathol       Date:  2008-08-07       Impact factor: 4.307

Review 9.  Monitoring of acromegaly: what should be performed when GH and IGF-1 levels are discrepant?

Authors:  Pamela U Freda
Journal:  Clin Endocrinol (Oxf)       Date:  2009-02-18       Impact factor: 3.478

10.  Hepatic-specific accessibility of Igf1 gene enhancers is independent of growth hormone signaling.

Authors:  Mahalakshmi Santhanam; Dennis J Chia
Journal:  Mol Endocrinol       Date:  2013-10-09
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