| Literature DB >> 17485249 |
Bruce A Barshop1, Jon A Gangoiti.
Abstract
The major coenzyme Q species in humans is the decaprenyl quinoid derivative coenzyme Q10 (CoQ10), and its measurement is somewhat challenging owing to its hydrophobicity and tendency to be oxidized. There are three major methods which are suited for analysis of CoQ10: HPLC-coupled UV or electrochemical detection, and tandem mass spectrometry. The techniques are discussed, and results of these applications to determine CoQ10 concentrations in various human fluids and tissues are summarized.Entities:
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Year: 2007 PMID： 17485249 DOI： 10.1016/j.mito.2007.04.002
Source DB: PubMed Journal: Mitochondrion ISSN： 1567-7249 Impact factor: 4.160