Literature DB >> 17484745

Does obesity prevent the needle from reaching muscle in intramuscular injections?

Ayten Zaybak1, Ulkü Yapucu Güneş, Sadik Tamsel, Leyla Khorshid, Ismet Eşer.   

Abstract

AIM: This paper is a report of a study to measure subcutaneous tissue thickness at the dorsogluteal and ventrogluteal sites and to determine optimal needle length for dorsogluteal and ventrogluteal intramuscular injections in adults with a body mass index of more than 24.9 kg/m2.
BACKGROUND: Problems can arise if drugs designed to be absorbed from muscle are only delivered into subcutaneous tissue. Increasing obesity in all developed and many developing countries makes this an increasing concern.
METHOD: Ultrasound measurements were made of the subcutaneous tissue of overweight, obese and extremely obese people at the dorsogluteal and ventrogluteal sites with the probe held at a 90 degrees angle to the plane of the injection site. Subcutaneous tissue thickness was measured in 119 adults whose body mass index was >or=25 kg/m2. The data were collected in 2005-2006.
RESULTS: Mean subcutaneous tissue thickness at the dorsogluteal site was 34.5 mm for overweight adults, 40.2 mm for obese adults and 51.4 mm for extremely obese adults, and at the ventrogluteal site was 38.2 mm for overweight adults, 43.1 mm for obese adults and 53.8 mm for extremely obese adults.
CONCLUSION: Intramuscular injections administered at the dorsogluteal site in 98% of women and 37% of men, and at the ventrogluteal site in 97% of women and 57% of men, would not reach the muscles of the buttock. A needle longer that 1.5 inches should be used in women whose body mass index is more than 24.9 kg/m2, the dorsogluteal site may be used in all overweight and obese men, and the ventrogluteal site may be used in overweight men only.

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Mesh:

Year:  2007        PMID: 17484745     DOI: 10.1111/j.1365-2648.2007.04264.x

Source DB:  PubMed          Journal:  J Adv Nurs        ISSN: 0309-2402            Impact factor:   3.187


  11 in total

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Authors:  Nachiket Shankar; Deepali Saxena; Pooja P Lokkur; Nikhil M Kumar; Neena Chris William; Nirupama Vijaykumar
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2.  Pharmacokinetics of human chorionic gonadotropin injection in obese and normal-weight women.

Authors:  Divya K Shah; Stacey A Missmer; Katharine F B Correia; Elizabeth S Ginsburg
Journal:  J Clin Endocrinol Metab       Date:  2014-01-29       Impact factor: 5.958

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4.  The appropriateness of the length of insulin needles based on determination of skin and subcutaneous fat thickness in the abdomen and upper arm in patients with type 2 diabetes.

Authors:  Kang Hee Sim; Moon Sook Hwang; Sun Young Kim; Hye Mi Lee; Ji Yeun Chang; Moon Kyu Lee
Journal:  Diabetes Metab J       Date:  2014-04-18       Impact factor: 5.376

5.  Analysis of gluteal subcutaneous and muscle thickness in infants and children for application to intramuscular injection, autologous fat grafting, and gluteal artery perforator flaps.

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Journal:  Biodes Manuf       Date:  2018-07-27

7.  Creating a change in the use of ventrogluteal site for intramuscular injection.

Authors:  Gülşah Gürol Arslan; Dilek Özden
Journal:  Patient Prefer Adherence       Date:  2018-09-13       Impact factor: 2.711

8.  Budget impact of somatostatin analogs as treatment for metastatic gastroenteropancreatic neuroendocrine tumors in US hospitals.

Authors:  Jesse D Ortendahl; Sonia J Pulgar; Beloo Mirakhur; David Cox; Tanya Gk Bentley; Alexandria T Phan
Journal:  Clinicoecon Outcomes Res       Date:  2017-08-16

9.  Assessment rate of true dorsogluteal intramuscular drug injection using ultrasonography.

Authors:  Ozkan Ozen; Mucahit Gunaydin; Aptekin Tosun; Zafer Unsal Coskun; Kursad Aytekin; Selcuk Takir
Journal:  Pak J Med Sci       Date:  2019 Jul-Aug       Impact factor: 1.088

10.  Evaluating the effectiveness of gluteal intramuscular injection sites: a cadaveric study.

Authors:  Yi-Suk Kim; Yong Seok Nam; Deog-Im Kim
Journal:  Anat Cell Biol       Date:  2022-03-31
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