Literature DB >> 17482437

[Impact of the rapid diagnosis downtown in the assumption of responsibility of the children in period of influenza].

R Cohen1, F Thollot, A Lécuyer, M Koskas, R Touitou, M Boucherat, P d'Athis, F Corrard, M Pecking, F de La Rocque.   

Abstract

Several studies in children showed at the paediatric emergency hospital the interest of influenza rapid diagnostic tests (IRDT) in this disease for which the clinical diagnosis is difficult in children. The purpose of this prospective study carried out in ambulatory paediatric setting was to evaluate impact of the IRDT in the assumption of responsibility of children suspected of Influenza infection. Thirty paediatricians (14 without IRDT, 16 with IRDT) included 602 children between 2004 and 2005. The influenza was confirmed by IRDT in 54% of the cases. Among the 13 symptoms or signs recorded, only 4 - chills (61.6 vs 48.4%), cough (89.8 vs 71.1%), rhinorrhea (97.9 vs 86.2%), and anorexia (50.3 vs 34.8%) - were significantly more frequent (P </= 0.01) for patients avec with positive IRDT. However, the difference is not sufficient to be contributive. The paediatricians using IRDT prescribed with positive test more oseltamivir (68.5 vs 1.9%, P < 0.0001). The antibiotic prescription was overall low (9.5% with IRDT vs 3.9% without IRDT, P = 0,008), and primarily when the result of IRDT was negative (15.7% if IRDT(-) vs 4.3% if IRDT(+), P = 0.0003). This study confirms the difficulty of clinical diagnosis, and shows the interest of IRDT for the diagnosis of influenza and consequently to improve the management of influenza in children in ambulatory paediatric setting.

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Year:  2007        PMID: 17482437     DOI: 10.1016/j.arcped.2007.02.087

Source DB:  PubMed          Journal:  Arch Pediatr        ISSN: 0929-693X            Impact factor:   1.180


  5 in total

Review 1.  Rapid viral diagnosis for acute febrile respiratory illness in children in the Emergency Department.

Authors:  Quynh Doan; Paul Enarson; Niranjan Kissoon; Terry P Klassen; David W Johnson
Journal:  Cochrane Database Syst Rev       Date:  2014-09-15

Review 2.  Cost-Effective Respiratory Virus Testing.

Authors:  B A Pinsky; R T Hayden
Journal:  J Clin Microbiol       Date:  2019-08-26       Impact factor: 5.948

3.  Cochrane Review: Rapid viral diagnosis for acute febrile respiratory illness in children in the Emergency Department.

Authors:  Quynh Doan; Paul Enarson; Niranjan Kissoon; Terry P Klassen; David W Johnson
Journal:  Evid Based Child Health       Date:  2010-06-24

4.  The Clinical Utility of Point-of-Care Tests for Influenza in Ambulatory Care: A Systematic Review and Meta-analysis.

Authors:  Joseph Jonathan Lee; Jan Y Verbakel; Clare Rosemary Goyder; Thanusha Ananthakumar; Pui San Tan; Phillip James Turner; Gail Hayward; Ann Van den Bruel
Journal:  Clin Infect Dis       Date:  2019-06-18       Impact factor: 9.079

5.  Clinical implications of aminotransferase elevation in hospitalised infants aged 8-90 days with respiratory virus detection.

Authors:  Sang Gyeom Kim; Yu Na Oh; Joon Kee Lee
Journal:  Influenza Other Respir Viruses       Date:  2020-03-10       Impact factor: 4.380

  5 in total

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