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Literature DB >> 17482308

Approaches to neural tissue engineering using scaffolds for drug delivery.

Stephanie M Willerth¹, Shelly E Sakiyama-Elbert.

Abstract

This review seeks to give an overview of the current approaches to drug delivery from scaffolds for neural tissue engineering applications. The challenges presented by attempting to replicate the three types of nervous tissue (brain, spinal cord, and peripheral nerve) are summarized. Potential scaffold materials (both synthetic and natural) and target drugs are discussed with the benefits and drawbacks given. Finally, common methods of drug delivery, including degradable/diffusion-based delivery systems, affinity-based delivery systems, immobilized drug delivery systems, and electrically controlled drug delivery systems, are examined and critiqued. Based on the current body of work, suggestions for future directions of research in the field of neural tissue engineering are presented.

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Year: 2007 PMID： 17482308 PMCID： PMC1976339 DOI： 10.1016/j.addr.2007.03.014

Source DB: PubMed Journal: Adv Drug Deliv Rev ISSN： 0169-409X Impact factor: 15.470

136 in total

Review 1. Neurotrophins: roles in neuronal development and function.

Authors: E J Huang; L F Reichardt
Journal: Annu Rev Neurosci Date: 2001 Impact factor: 12.449

2. Photofabricated gelatin-based nerve conduits: nerve tissue regeneration potentials.

Authors: Eduardo Gámez; Yoshinobu Goto; Kengo Nagata; Toru Iwaki; Tomio Sasaki; Takehisa Matsuda
Journal: Cell Transplant Date: 2004 Impact factor: 4.064

3. Fast-gelling injectable blend of hyaluronan and methylcellulose for intrathecal, localized delivery to the injured spinal cord.

Authors: Dimpy Gupta; Charles H Tator; Molly S Shoichet
Journal: Biomaterials Date: 2005-12-01 Impact factor: 12.479

Review 4. BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis.

Authors: Clive R Bramham; Elhoucine Messaoudi
Journal: Prog Neurobiol Date: 2005-06 Impact factor: 11.685

5. The enhancement of cell adherence and inducement of neurite outgrowth of dorsal root ganglia co-cultured with hyaluronic acid hydrogels modified with Nogo-66 receptor antagonist in vitro.

Authors: S Hou; W Tian; Q Xu; F Cui; J Zhang; Q Lu; C Zhao
Journal: Neuroscience Date: 2005-11-17 Impact factor: 3.590

6. Clinical long-term in vivo evaluation of poly(L-lactic acid) porous conduits for peripheral nerve regeneration.

Authors: G R Evans; K Brandt; A D Niederbichler; P Chauvin; S Herrman; M Bogle; L Otta; B Wang; C W Patrick
Journal: J Biomater Sci Polym Ed Date: 2000 Impact factor: 3.517

7. Intracranial delivery of recombinant nerve growth factor: release kinetics and protein distribution for three delivery systems.

Authors: W M Saltzman; M W Mak; M J Mahoney; E T Duenas; J L Cleland
Journal: Pharm Res Date: 1999-02 Impact factor: 4.200

8. Combinatorial therapy with neurotrophins and cAMP promotes axonal regeneration beyond sites of spinal cord injury.

Authors: Paul Lu; Hong Yang; Leonard L Jones; Marie T Filbin; Mark H Tuszynski
Journal: J Neurosci Date: 2004-07-14 Impact factor: 6.167

9. Exogenous fibrin matrix precursors stimulate the temporal progress of nerve regeneration within a silicone chamber.

Authors: L R Williams
Journal: Neurochem Res Date: 1987-10 Impact factor: 3.996

10. Collagen containing neurotrophin-3 (NT-3) attracts regrowing injured corticospinal axons in the adult rat spinal cord and promotes partial functional recovery.

Authors: D A Houweling; A J Lankhorst; W H Gispen; P R Bär; E A Joosten
Journal: Exp Neurol Date: 1998-09 Impact factor: 5.330

63 in total

Review 1. Biomaterial Approaches to Modulate Reactive Astroglial Response.

Authors: Jonathan M Zuidema; Ryan J Gilbert; Manoj K Gottipati
Journal: Cells Tissues Organs Date: 2018-12-05 Impact factor: 2.481

2. Vascular endothelial growth factor and fibroblast growth factor 2 delivery from spinal cord bridges to enhance angiogenesis following injury.

Authors: Laura De Laporte; Anne des Rieux; Hannah M Tuinstra; Marina L Zelivyanskaya; Nora M De Clerck; Andrei A Postnov; Véronique Préat; Lonnie D Shea
Journal: J Biomed Mater Res A Date: 2011-05-31 Impact factor: 4.396

Approaches to neural tissue engineering using scaffolds for drug delivery.

Review 1. Neurotrophins: roles in neuronal development and function.

2. Photofabricated gelatin-based nerve conduits: nerve tissue regeneration potentials.

3. Fast-gelling injectable blend of hyaluronan and methylcellulose for intrathecal, localized delivery to the injured spinal cord.

Review 4. BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis.

5. The enhancement of cell adherence and inducement of neurite outgrowth of dorsal root ganglia co-cultured with hyaluronic acid hydrogels modified with Nogo-66 receptor antagonist in vitro.

6. Clinical long-term in vivo evaluation of poly(L-lactic acid) porous conduits for peripheral nerve regeneration.

7. Intracranial delivery of recombinant nerve growth factor: release kinetics and protein distribution for three delivery systems.

8. Combinatorial therapy with neurotrophins and cAMP promotes axonal regeneration beyond sites of spinal cord injury.

9. Exogenous fibrin matrix precursors stimulate the temporal progress of nerve regeneration within a silicone chamber.

10. Collagen containing neurotrophin-3 (NT-3) attracts regrowing injured corticospinal axons in the adult rat spinal cord and promotes partial functional recovery.

Review 1. Biomaterial Approaches to Modulate Reactive Astroglial Response.

2. Vascular endothelial growth factor and fibroblast growth factor 2 delivery from spinal cord bridges to enhance angiogenesis following injury.

3. Use of Erythropoietin as adjuvant therapy in nerve reconstruction.

4. Plasmid releasing multiple channel bridges for transgene expression after spinal cord injury.

Review 5. Biomaterial design strategies for the treatment of spinal cord injuries.

6. Drug sorption onto and release from soy protein fibers.

7. Photoresponsive microvalve for remote actuation and flow control in microfluidic devices.

8. Three Dimensional Conjugation of Recombinant N-Cadherin to a Hydrogel for In Vitro Anisotropic Neural Growth.

Review 9. Hydrogels in spinal cord injury repair strategies.

10. Adhesion molecule-modified biomaterials for neural tissue engineering.