PURPOSE: Preventing gap or rupture is important to achieving a successful outcome after tendon repair. Weak sutures break; strong sutures fail by pull-out at the tendon-suture interface. In this study, we investigated the use of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC) and cyanoacrylate to enhance the strength of the tendon-suture interface. METHODS: Twenty-four canine flexor digitorum profundus tendons were used to test EDC and cyanoacrylate reinforcement methods, with 12 tendons in each group. A single-loop suture technique was used to test the tendon-suture interface strength. RESULTS: The mean ultimate strengths of the EDC group and the cyanoacrylate group were significantly higher than those of their respective control groups. The stiffness of the group with cyanoacrylate-augmented loops was significantly higher than that of its respective control group. There was no significant difference in stiffness between the 2 reinforcement methods. CONCLUSIONS: Our results suggest that tendon-suture interface reinforcement may improve the pull-out failure strength of a suture construct and thereby increase the effectiveness of stronger suture materials. Future studies might address the effects of different kinds and methods of reinforcement with various suture materials and constructs and in different tissues.
PURPOSE: Preventing gap or rupture is important to achieving a successful outcome after tendon repair. Weak sutures break; strong sutures fail by pull-out at the tendon-suture interface. In this study, we investigated the use of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC) and cyanoacrylate to enhance the strength of the tendon-suture interface. METHODS: Twenty-four canine flexor digitorum profundus tendons were used to test EDC and cyanoacrylate reinforcement methods, with 12 tendons in each group. A single-loop suture technique was used to test the tendon-suture interface strength. RESULTS: The mean ultimate strengths of the EDC group and the cyanoacrylate group were significantly higher than those of their respective control groups. The stiffness of the group with cyanoacrylate-augmented loops was significantly higher than that of its respective control group. There was no significant difference in stiffness between the 2 reinforcement methods. CONCLUSIONS: Our results suggest that tendon-suture interface reinforcement may improve the pull-out failure strength of a suture construct and thereby increase the effectiveness of stronger suture materials. Future studies might address the effects of different kinds and methods of reinforcement with various suture materials and constructs and in different tissues.
Authors: Chunfeng Zhao; Yasuhiro Ozasa; Haruhiko Shimura; Ramona L Reisdorf; Andrew R Thoreson; Gregory Jay; Steven L Moran; Kai-Nan An; Peter C Amadio Journal: J Orthop Res Date: 2015-07-31 Impact factor: 3.494
Authors: Xiaoxi Ji; Ramona L Reisdorf; Andrew R Thoreson; Lawrence R Berglund; Steven L Moran; Gregory D Jay; Kai-Nan An; Peter C Amadio; Chunfeng Zhao Journal: J Bone Joint Surg Am Date: 2015-06-17 Impact factor: 5.284
Authors: Jin Qu; Andrew R Thoreson; Qingshan Chen; Kai-Nan An; Peter C Amadio; Chunfeng Zhao Journal: J Orthop Res Date: 2013-08-12 Impact factor: 3.494
Authors: Mehmet Murat Bala; Abdullah Alper Şahin; Mehmet Boz; Yasin Durukan; Tülin Fırat; Murat Pakdil; Kutay Engin Özturan Journal: Med Sci Monit Date: 2021-09-06