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Literature DB >> 17481551

5-lipoxygenase: regulation and possible involvement in atherosclerosis.

Abstract

This review article focuses on two aspects regarding 5-lipoxygenase. First, mechanisms for activation of the enzyme. Second, the involvement of 5-lipoxygenase and leukotrienes in atherosclerosis.

Entities: Chemical Disease Gene

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Year: 2007 PMID： 17481551 DOI： 10.1016/j.prostaglandins.2007.01.003

Source DB: PubMed Journal: Prostaglandins Other Lipid Mediat ISSN： 1098-8823 Impact factor: 3.072

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Cited

20 in total

1. Leukotriene B4 receptor-1 mediates intermittent hypoxia-induced atherogenesis.

Authors: Richard C Li; Bodduluri Haribabu; Steven P Mathis; Jinkwan Kim; David Gozal
Journal: Am J Respir Crit Care Med Date: 2011-04-14 Impact factor: 21.405

2. Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.

Authors: Victor Kenyon; Ganesha Rai; Ajit Jadhav; Lena Schultz; Michelle Armstrong; J Brian Jameson; Steven Perry; Netra Joshi; James M Bougie; William Leister; David A Taylor-Fishwick; Jerry L Nadler; Michael Holinstat; Anton Simeonov; David J Maloney; Theodore R Holman
Journal: J Med Chem Date: 2011-07-08 Impact factor: 7.446

3. Anti-inflammatory activity of copao (Eulychnia acida Phil., Cactaceae) fruits.

Authors: Felipe Jiménez-Aspee; Maria Rosa Alberto; Cristina Quispe; Maria del Pilar Caramantin Soriano; Cristina Theoduloz; Iris Catiana Zampini; Maria Ines Isla; Guillermo Schmeda-Hirschmann
Journal: Plant Foods Hum Nutr Date: 2015-06 Impact factor: 3.921

Review 4. Polyunsaturated fatty acids and cardiovascular disease: implications for nutrigenetics.

Authors: Hooman Allayee; Nitzan Roth; Howard N Hodis
Journal: J Nutrigenet Nutrigenomics Date: 2009-09-23

Review 5. Leukotrienes in atherosclerosis: new target insights and future therapy perspectives.

Authors: Graziano Riccioni; Alessandra Zanasi; Nicola Vitulano; Barbara Mancini; Nicolantonio D'Orazio
Journal: Mediators Inflamm Date: 2010-01-26 Impact factor: 4.711

6. Effects of MK-886, a 5-lipoxygenase activating protein (FLAP) inhibitor, and 5-lipoxygenase deficiency on the forced swimming behavior of mice.

Authors: Tolga Uz; Nikola Dimitrijevic; Marta Imbesi; Hari Manev; Radmila Manev
Journal: Neurosci Lett Date: 2008-03-21 Impact factor: 3.046

5-lipoxygenase: regulation and possible involvement in atherosclerosis.

1. Leukotriene B4 receptor-1 mediates intermittent hypoxia-induced atherogenesis.

2. Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.

3. Anti-inflammatory activity of copao (Eulychnia acida Phil., Cactaceae) fruits.

Review 4. Polyunsaturated fatty acids and cardiovascular disease: implications for nutrigenetics.

Review 5. Leukotrienes in atherosclerosis: new target insights and future therapy perspectives.

6. Effects of MK-886, a 5-lipoxygenase activating protein (FLAP) inhibitor, and 5-lipoxygenase deficiency on the forced swimming behavior of mice.

7. The Role of Immunogenicity in Cardiovascular Disease.

Review 8. The LDL modification hypothesis of atherogenesis: an update.

9. The 5-lipoxygenase as a common pathway for pathological brain and vascular aging.

10. 5-Lipoxygenase DNA methylation and mRNA content in the brain and heart of young and old mice.