Literature DB >> 17481486

TIPS in Florida: is its application a result of evidence-based medicine?

Alexander S Rosemurgy1, Daniel L Molloy, Donald P Thometz, Desiree V Villadolid, Sarah M Cowgill, Emmanuel E Zervos.   

Abstract

BACKGROUND: The typical resident in surgery in the US will not care for a patient with advanced portal hypertension and will not participate in a portacaval shunt. The aim of this study is to compare the number of transjugular intrahepatic portasystemic stent shunts (TIPS) with the number of surgical shunts undertaken in the State of Florida and to assess whether these numbers are consistent with today's evidence-based medicine.
METHODS: We examined the database of the Agency for Health Care Administration of the State of Florida from January 1, 2002, through September 30, 2005, for "intraabdominal venous shunt" (ICD-9 code, 39.1). Data collected include "case mix," "case severity," length of stay, total gross charges, and discharge status. Conclusions about longterm survival from a prospective randomized clinical trial comparing TIPS to surgical shunting were applied to this dataset to determine if the relative frequency of TIPS application in Florida was supported by evidence-based medicine.
RESULTS: TIPS was undertaken more than 12 times as often as surgical shunting (860 patients versus 70 patients). After TIPS versus surgical shunts, average length of stay and hospital charges were less, but case mix, case severity, and in-hospital mortality (11.4% for each) were not different. Applying survival data from a randomized trial comparing TIPS with surgical shunting to the State of Florida database, 129 more people (p < 0.0001) would be alive at 2 years and 137 more (p < 0.0001) would be alive at 5 years after shunting if surgical shunts had been used in lieu of TIPS.
CONCLUSIONS: TIPS leads to shorter hospitalizations and reduced hospital charges and is applied in numbers much greater than surgical shunts, despite evidence that suggests inferior longterm efficacy and survival. Current application of TIPS is not a result of evidence-based medicine, and application of surgical shunting is encouraged.

Entities:  

Mesh:

Year:  2007        PMID: 17481486     DOI: 10.1016/j.jamcollsurg.2007.01.014

Source DB:  PubMed          Journal:  J Am Coll Surg        ISSN: 1072-7515            Impact factor:   6.113


  7 in total

Review 1.  [Portosystemic shunt surgery between TIPS and liver transplantation].

Authors:  G Puhl; S Gül; P Neuhaus
Journal:  Chirurg       Date:  2011-10       Impact factor: 0.955

2.  Randomized controlled trial of emergency transjugular intrahepatic portosystemic shunt versus emergency portacaval shunt treatment of acute bleeding esophageal varices in cirrhosis.

Authors:  Marshall J Orloff; Florin Vaida; Kevin S Haynes; Robert J Hye; Jon I Isenberg; Horacio Jinich-Brook
Journal:  J Gastrointest Surg       Date:  2012-09-25       Impact factor: 3.452

3.  Portosystemic Shunts: Stable Utilization and Improved Outcomes, Two Decades After the Transjugular Intrahepatic Portosystemic Shunt.

Authors:  Brandon C Perry; Sharon W Kwan
Journal:  J Am Coll Radiol       Date:  2015-09-26       Impact factor: 5.532

Review 4.  Update on Shunt Surgery.

Authors:  Tim R Glowka; Jörg C Kalff; Steffen Manekeller
Journal:  Visc Med       Date:  2020-04-14

5.  Portosystemic shunt surgery in the era of TIPS: imaging-based planning of the surgical approach.

Authors:  Uli Fehrenbach; Safak Gül-Klein; Miguel de Sousa Mendes; Ingo Steffen; Julienne Stern; Dominik Geisel; Gero Puhl; Timm Denecke
Journal:  Abdom Radiol (NY)       Date:  2020-06-05

Review 6.  Clinical Management of Chronic Portal/Mesenteric Vein Thrombosis: The Surgeon's Point of View.

Authors:  Tim R Glowka; Jörg C Kalff; Nico Schäfer
Journal:  Viszeralmedizin       Date:  2014-12

7.  Transjugular intrahepatic portosystemic shunt versus surgical shunting in the management of portal hypertension.

Authors:  Long Huang; Qing-Sheng Yu; Qi Zhang; Ju-Da Liu; Zhen Wang
Journal:  Chin Med J (Engl)       Date:  2015-03-20       Impact factor: 2.628

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.