Literature DB >> 17478209

Age-related changes in human laryngeal nerves.

Romualdo Tiago1, Paulo Pontes, Osíris Camponês do Brasil.   

Abstract

OBJECTIVES: We sought to perform a morphometric analysis of myelinated fibers from laryngeal nerves with the aim of verifying quantitative changes due to the aging process.
METHODS: A 1-cm fragment was collected from the superior laryngeal nerves and recurrent laryngeal nerves from 12 cadavers during autopsy. The sample was divided in two groups: an adult group (aged <60 years) and an elderly group (aged > or =60 years).
RESULTS: The total number of myelinated fibers from the superior laryngeal nerves was similar in both groups (adult group = 9017 +/- 1692, elderly group = 7918 +/- 1624; P = 0.79). The adult group had a higher total number of myelinated fibers in the recurrent laryngeal nerves than that of the elderly group (adult group = 3276 +/- 383, elderly group = 2381 +/- 669; P = 0.005), as well as a higher total number of fibers in the laryngeal nerves (both superior and recurrent) than the elderly group (P = 0.02).
CONCLUSIONS: The adult group has a higher total number of myelinated fibers in the laryngeal nerves than the elderly group.

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Year:  2007        PMID: 17478209     DOI: 10.1016/j.otohns.2006.11.054

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   3.497


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