Literature DB >> 17476191

Biomechanical comparison of callus over a locked intramedullary nail in various segmental bone defects in a sheep model.

Minos Tyllianakis1, Despina Deligianni, Andreas Panagopoulos, Michael Pappas, Efrosini Sourgiadaki, Demosthenis Mavrilas, Andreas Papadopoulos.   

Abstract

BACKGROUND: Little has been written about the size of a bone defect that can be restored with one-stage lengthening over a reamed intramedullary nail. MATERIAL/
METHODS: Sixteen adult female sheep were divided into four main groups: a simple osteotomy group (group I) and three segmental defect groups (1-, 2-, and 3-cm gaps, groups II-IV). One intact left tibia from each group was also used as the non-osteotomized intact control group (group V). In all cases, the osteotomy was fixed with an interlocked Universal Humeral Nail after reaming to 7 mm. Healing of the osteotomies was evaluated after 16 weeks by biomechanical testing. The examined parameters were torsional stiffness, shear stress, and angle of torsion at the time of fracture.
RESULTS: The regenerate bone obvious in x-rays in the groups with 1- and 2-cm gaps had considerable mechanical properties. Torsional stiffness in these two groups was nearly equal and its value was about 60% of the stiffness of the simple osteotomy group. Gradually decreasing stiffness was observed as the osteotomy gap increased. No significant differences were found among the angles of torsion at fracture for the various osteotomies or the intact bone. These results showed that the group with 1-cm gap had 65% of the shear stress at failure of the simple osteotomy group.
CONCLUSIONS: The authors believe that there is evidence indicating that intramedullary nailing could be a reasonable option when one-stage lengthening of a long bone by 1 or 2 cm is contemplated.

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Year:  2007        PMID: 17476191

Source DB:  PubMed          Journal:  Med Sci Monit        ISSN: 1234-1010


  2 in total

1.  A preclinical large-animal model for the assessment of critical-size load-bearing bone defect reconstruction.

Authors:  David S Sparks; Siamak Saifzadeh; Flavia Medeiros Savi; Constantin E Dlaska; Arne Berner; Jan Henkel; Johannes C Reichert; Martin Wullschleger; Jiongyu Ren; Amaia Cipitria; Jacqui A McGovern; Roland Steck; Michael Wagels; Maria Ann Woodruff; Michael A Schuetz; Dietmar W Hutmacher
Journal:  Nat Protoc       Date:  2020-02-14       Impact factor: 13.491

2.  Temporal Changes in Reverse Torque of Locking-Head Screws Used in the Locking Plate in Segmental Tibial Defect in Goat Model.

Authors:  Remigiusz M Grzeskowiak; Rebecca E Rifkin; Elizabeth G Croy; Richard C Steiner; Reza Seddighi; Pierre-Yves Mulon; Henry S Adair; David E Anderson
Journal:  Front Surg       Date:  2021-04-27
  2 in total

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