N Miyakoshi1, M Hongo, S Maekawa, Y Ishikawa, Y Shimada, E Itoi. 1. Division of Orthopedic Surgery, Department of Neuro and Locomotor Science, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan. miyakosh@doc.med.akita-u.ac.jp
Abstract
UNLABELLED: To assess the effect of multiple factors on quality of life (QOL) in osteoporosis, relationships between the QOL and possible spinal factors were analyzed in 174 postmenopausal women with osteoporosis. Back extensor strength and lumbar spinal mobility were the most important factors for QOL in these patients. INTRODUCTION: Quality of life (QOL) in patients with osteoporosis and vertebral fractures is impaired by the decline of total spinal mobility, although it is not clear to what extent. This study aimed to assess the effect of multiple factors on QOL in patients with osteoporosis. METHODS: QOL of 174 postmenopausal women with osteoporosis (mean, 68 years old) was evaluated using the Japanese Osteoporosis QOL Questionnaire (JOQOL). Correlations between the JOQOL score, bone mineral density (BMD) of the lumbar spine/proximal femur/whole body, the kyphosis angle and mobility of thoracic and lumbar spine, the number of vertebral fractures, grip strengths of dominant and non-dominant hands, and isometric back extensor strength (BES) were analyzed. RESULTS: JOQOL showed significant correlation (p < 0.05) with age (r = -0.303), BES (r = 0.455), dominant and non-dominant grip strengths (r = 0.273 and r = 0.255, respectively), number of vertebral fractures (r = -0.282), BMDs of proximal femur and whole body (r = 0.200 and r = 0.157, respectively), lumbar kyphosis angle (r = -0.296), and lumbar spinal mobility (r = 0.345). Multiple regression analysis revealed that the BES and lumbar spinal mobility were the significant contributors to the JOQOL (p < 0.05). CONCLUSION: BES and lumbar spinal mobility are the important factors for QOL in patients with postmenopausal osteoporosis.
UNLABELLED: To assess the effect of multiple factors on quality of life (QOL) in osteoporosis, relationships between the QOL and possible spinal factors were analyzed in 174 postmenopausal women with osteoporosis. Back extensor strength and lumbar spinal mobility were the most important factors for QOL in these patients. INTRODUCTION: Quality of life (QOL) in patients with osteoporosis and vertebral fractures is impaired by the decline of total spinal mobility, although it is not clear to what extent. This study aimed to assess the effect of multiple factors on QOL in patients with osteoporosis. METHODS: QOL of 174 postmenopausal women with osteoporosis (mean, 68 years old) was evaluated using the Japanese Osteoporosis QOL Questionnaire (JOQOL). Correlations between the JOQOL score, bone mineral density (BMD) of the lumbar spine/proximal femur/whole body, the kyphosis angle and mobility of thoracic and lumbar spine, the number of vertebral fractures, grip strengths of dominant and non-dominant hands, and isometric back extensor strength (BES) were analyzed. RESULTS: JOQOL showed significant correlation (p < 0.05) with age (r = -0.303), BES (r = 0.455), dominant and non-dominant grip strengths (r = 0.273 and r = 0.255, respectively), number of vertebral fractures (r = -0.282), BMDs of proximal femur and whole body (r = 0.200 and r = 0.157, respectively), lumbar kyphosis angle (r = -0.296), and lumbar spinal mobility (r = 0.345). Multiple regression analysis revealed that the BES and lumbar spinal mobility were the significant contributors to the JOQOL (p < 0.05). CONCLUSION: BES and lumbar spinal mobility are the important factors for QOL in patients with postmenopausal osteoporosis.
Authors: J D Adachi; G Loannidis; C Berger; L Joseph; A Papaioannou; L Pickard; E A Papadimitropoulos; W Hopman; S Poliquin; J C Prior; D A Hanley; W P Olszynski; T Anastassiades; J P Brown; T Murray; S A Jackson; A Tenenhouse Journal: Osteoporos Int Date: 2001 Impact factor: 4.507
Authors: P Lips; C Cooper; D Agnusdei; F Caulin; P Egger; O Johnell; J A Kanis; S Kellingray; A Leplege; U A Liberman; E McCloskey; H Minne; J Reeve; J Y Reginster; M Scholz; C Todd; M C de Vernejoul; I Wiklund Journal: Osteoporos Int Date: 1999 Impact factor: 4.507
Authors: Deborah M Kado; Mei-Hua Huang; Elizabeth Barrett-Connor; Gail A Greendale Journal: J Gerontol A Biol Sci Med Sci Date: 2005-05 Impact factor: 6.053
Authors: M Naves; J B Díaz-López; C Gómez; A Rodríguez-Rebollar; M Rodríguez-García; J B Cannata-Andía Journal: Osteoporos Int Date: 2003-04-25 Impact factor: 4.507
Authors: D M Kado; T Duong; K L Stone; K E Ensrud; M C Nevitt; G A Greendale; S R Cummings Journal: Osteoporos Int Date: 2003-06-24 Impact factor: 4.507
Authors: Jonathan D Adachi; George Ioannidis; Wojciech P Olszynski; Jacques P Brown; David A Hanley; Rolf J Sebaldt; Annie Petrie; Alan Tenenhouse; Gregory F Stephenson; Alexandra Papaioannou; Gordon H Guyatt; Charlie H Goldsmith Journal: BMC Musculoskelet Disord Date: 2002-04-22 Impact factor: 2.362
Authors: Katelyn A Burkhart; Alexander G Bruno; Mary L Bouxsein; Jonathan F Bean; Dennis E Anderson Journal: J Orthop Res Date: 2017-06-28 Impact factor: 3.494
Authors: Shuko Nojiri; Russel T Burge; Jennifer A Flynn; Shonda A Foster; Hideaki Sowa Journal: J Bone Miner Metab Date: 2013-03-28 Impact factor: 2.626