Literature DB >> 17456753

Treating the lesions, not the disease.

Xiongwei Zhu1, Jesus Avila, George Perry, Mark A Smith.   

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Year:  2007        PMID： 17456753      PMCID： PMC1854942          DOI： 10.2353/ajpath.2007.070193

Source DB:  PubMed          Journal:  Am J Pathol        ISSN： 0002-9440            Impact factor:   4.307


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  26 in total

1.  Amyloid-beta junkies.

Authors:  G Perry; A Nunomura; A K Raina; M A Smith
Journal:  Lancet       Date:  2000-02-26       Impact factor: 79.321

2.  Predicting the failure of amyloid-beta vaccine.

Authors:  Mark A Smith; Craig S Atwood; James A Joseph; George Perry
Journal:  Lancet       Date:  2002-05-25       Impact factor: 79.321

3.  Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction.

Authors:  Salvatore Oddo; Antonella Caccamo; Jason D Shepherd; M Paul Murphy; Todd E Golde; Rakez Kayed; Raju Metherate; Mark P Mattson; Yama Akbari; Frank M LaFerla
Journal:  Neuron       Date:  2003-07-31       Impact factor: 17.173

Review 4.  Copernicus revisited: amyloid beta in Alzheimer's disease.

Authors:  J Joseph; B Shukitt-Hale; N A Denisova; A Martin; G Perry; M A Smith
Journal:  Neurobiol Aging       Date:  2001 Jan-Feb       Impact factor: 4.673

5.  Oxidative damage is the earliest event in Alzheimer disease.

Authors:  A Nunomura; G Perry; G Aliev; K Hirai; A Takeda; E K Balraj; P K Jones; H Ghanbari; T Wataya; S Shimohama; S Chiba; C S Atwood; R B Petersen; M A Smith
Journal:  J Neuropathol Exp Neurol       Date:  2001-08       Impact factor: 3.685

6.  Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss.

Authors:  A Takeuchi; M C Irizarry; K Duff; T C Saido; K Hsiao Ashe; M Hasegawa; D M Mann; B T Hyman; T Iwatsubo
Journal:  Am J Pathol       Date:  2000-07       Impact factor: 4.307

7.  Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease.

Authors:  A Goate; M C Chartier-Harlin; M Mullan; J Brown; F Crawford; L Fidani; L Giuffra; A Haynes; N Irving; L James
Journal:  Nature       Date:  1991-02-21       Impact factor: 49.962

8.  Tau filament formation in transgenic mice expressing P301L tau.

Authors:  J Götz; F Chen; R Barmettler; R M Nitsch
Journal:  J Biol Chem       Date:  2001-01-05       Impact factor: 5.157

9.  Lithium reduces tau phosphorylation but not A beta or working memory deficits in a transgenic model with both plaques and tangles.

Authors:  Antonella Caccamo; Salvatore Oddo; Lana X Tran; Frank M LaFerla
Journal:  Am J Pathol       Date:  2007-05       Impact factor: 4.307

Review 10.  The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics.

Authors:  John Hardy; Dennis J Selkoe
Journal:  Science       Date:  2002-07-19       Impact factor: 47.728
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  4 in total

Review 1.  Hyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer disease.

Authors:  C-X Gong; K Iqbal
Journal:  Curr Med Chem       Date:  2008       Impact factor: 4.530

Review 2.  Alternative neural circuitry that might be impaired in the development of Alzheimer disease.

Authors:  Jesus Avila; George Perry; Bryan A Strange; Felix Hernandez
Journal:  Front Neurosci       Date:  2015-04-23       Impact factor: 4.677

3.  Chronic neuroinflammation in Alzheimer's disease: new perspectives on animal models and promising candidate drugs.

Authors:  Christopher Millington; Sandra Sonego; Niloo Karunaweera; Alejandra Rangel; Janice R Aldrich-Wright; Iain L Campbell; Erika Gyengesi; Gerald Münch
Journal:  Biomed Res Int       Date:  2014-06-16       Impact factor: 3.411

Review 4.  Neurobiological pathways to Alzheimer's disease: Amyloid-beta, TAU protein or both?

Authors:  Vanessa de Jesus R de Paula; Fabiana Meira Guimarães; Breno Satler Diniz; Orestes Vicente Forlenza
Journal:  Dement Neuropsychol       Date:  2009 Jul-Sep
  4 in total

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