| Literature DB >> 17448658 |
Michael Johnson1, An-Rong Li, Jiwen Liu, Zice Fu, Liusheng Zhu, Shichang Miao, Xuemei Wang, Qingge Xu, Alan Huang, Andrew Marcus, Feng Xu, Karen Ebsworth, Emmanuel Sablan, Jay Danao, Jeff Kumer, Dan Dairaghi, Chris Lawrence, Tim Sullivan, George Tonn, Thomas Schall, Tassie Collins, Julio Medina.
Abstract
A series of quinazolinone-derived inhibitors of the CXCR3 receptor have been synthesized and their affinity for the receptor evaluated. Compounds were evaluated in a (125)I-IP10 displacement assay and in in vitro cell migration assays to IP10, ITAC, and MIG using human peripheral blood mononuclear cells.Entities:
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Year: 2007 PMID： 17448658 DOI： 10.1016/j.bmcl.2007.03.106
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823