| Literature DB >> 17445313 |
P P Chapagain1, J S van Kessel, J S Karns, D R Wolfgang, E Hovingh, K A Nelen, Y H Schukken, Y T Grohn.
Abstract
We developed a mathematical model of the transmission dynamics of salmonella to describe an outbreak of S. Cerro infection that occurred in a Pennsylvania dairy herd. The data were collected as part of a cooperative research project between the Regional Dairy Quality Management Alliance and the Agricultural Research Service. After the initial detection of a high prevalence of S. Cerro infection in the herd, a frequent and intensive sampling was conducted and the outbreak was followed for 1 year. The data showed a persistent presence of S. Cerro with a high prevalence of infection in the herd. The dynamics of host and pathogen were modelled using a set of nonlinear differential equations. A more realistically distributed (gamma-distributed) infectious period using multiple stages of infection was considered. The basic reproduction number was calculated and relevance to the intervention strategies is discussed.Entities:
Mesh：
Year: 2007 PMID： 17445313 PMCID： PMC2870801 DOI： 10.1017/S0950268807008400
Source DB: PubMed Journal: Epidemiol Infect ISSN： 0950-2688 Impact factor: 2.451