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Literature DB >> 174413

A model for the quantitative study of Arthus (immunologic) hypersensitivity in rats.

S Yamamoto, C J Dunn, D A Deporter, F Capasso, D A Willoughby, E C Huskinsson.

Abstract

A model of reverse passive Arthus (RPA) reaction in the pleural cavity of rats is described. The time course of development of exudate and migration of cells has been examined. It has been found to be complement dependent and dominated by polymorphonuclear cells. The reaction reaches a peak around 6 hours after challenge. Cyclic AMP levels have been measured both intracellularly and extracellularly and have been found to persist at high levels after the waning of the reaction.

Entities: Chemical Disease Species

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Year: 1975 PMID： 174413 DOI： 10.1007/bf02205246

Source DB: PubMed Journal: Agents Actions ISSN： 0065-4299

10 in total

1. Quantitative studies on cell-mediated immunity in the pleural cavity of guinea-pigs.

Authors: S Yamamoto; C J Dunn; F Capasso; D A Deporter; D A Willoughby
Journal: J Pathol Date: 1975-10 Impact factor: 7.996

2. Further studies on carrageenan-induced pleurisy in rats.

Authors: F Capasso; C J Dunn; S Yamamoto; D A Willoughby; J P Giroud
Journal: J Pathol Date: 1975-06 Impact factor: 7.996

3. Diagnostic complement fixation. I. A method.

Authors: A G OSLER; J H STRAUSS; M M MAYER
Journal: Am J Syph Gonorrhea Vener Dis Date: 1952-03

4. Cyclic AMP, ATP, and reversed anaphylactic histamine release from rat mast cells.

Authors: M Kaliner; K F Austen
Journal: J Immunol Date: 1974-02 Impact factor: 5.422

5. Depletion of plasma complement in vivo by a protein of cobra venom: its effect on various immunologic reactions.

Authors: C G Cochrane; H J Müller-Eberhard; B S Aikin
Journal: J Immunol Date: 1970-07 Impact factor: 5.422

6. Distribution of prostaglandins in inflammatory exudate.

Authors: G P Velo; C J Dunn; J P Giroud; J Timsit; D A Willoughby
Journal: J Pathol Date: 1973-11 Impact factor: 7.996

7. Two anticomplementary factors in cobra venom: hemolysis of guinea pig erythrocytes by one of them.

Authors: M Ballow; C G Cochrane
Journal: J Immunol Date: 1969-11 Impact factor: 5.422

8. Use of the reversed passive Arthus reaction as a test for anti-inflammatory agents.

Authors: M B Goldlust; W F Schreiber
Journal: Agents Actions Date: 1975-02

9. A physiologic differentiation between delayed and immediate hypersensitivity.

Authors: M A Apicella; J C Allen
Journal: J Clin Invest Date: 1969-02 Impact factor: 14.808

10. Mechanisms of lysosomal enzyme release from human leukocytes. II. Effects of cAMP and cGMP, autonomic agonists, and agents which affect microtubule function.

Authors: R B Zurier; G Weissmann; S Hoffstein; S Kammerman; H H Tai
Journal: J Clin Invest Date: 1974-01 Impact factor: 14.808

10 in total

18 in total

1. Protease inhibitors reduce the reverse passive Arthus reaction.

Authors: Y G Hyman; T L Vischer
Journal: Agents Actions Date: 1978-10

2. Cyclic adenosine 3', 5'-monophosphate and the mechanism of action of three common anti-inflammatory drugs.

Authors: D A Deporter; C J Dunn; D A Willoughby
Journal: Br J Pharmacol Date: 1979-02 Impact factor: 8.739

3. Professor Derek Albert Willoughby (1930-2004).

Authors: K D Rainsford
Journal: Inflammopharmacology Date: 2005 Impact factor: 4.473

4. Leukotriene B4 production and pharmacologic regulation of reverse passive Arthus pleurisy: importance of antigen dose.

Authors: B M Weichman; J W Berkenkopf; C A Cullinan; R J Sturm
Journal: Agents Actions Date: 1987-08