Literature DB >> 17437118

The use of Surgisis for abdominal wall reconstruction in the separation of omphalopagus conjoined twins.

Roshni Dasgupta1, Paul W Wales, Ronald M Zuker, David M Fisher, Jacob C Langer.   

Abstract

Abdominal wall reconstruction in omphalopagus twins poses a difficult reconstructive challenge, as separation often results in a large abdominal wall defect. A number of options are available for closure, including tissue flaps, expanders and patches made of foreign material. Surgisis is a new biodegradable small intestine scaffolding substrate that permits tissue in-growth and results in a permanent durable scar. We describe its use in abdominal wall reconstruction after separation of a set of conjoined twins. A set of omphalopagus conjoined twins shared liver and abdominal wall. After separation at 6 months of age, Twin A's abdomen could be closed primarily, but Twin B could not. A 4-ply Surgisis mesh was used in the upper abdominal closure, and a skin flap was created, to completely cover the patch. Both twins survived the operation. A small portion of the skin flap over the Surgisis broke down, healing by secondary intention. In follow up of over 18 months post procedure, there have been no wound infections and the abdominal wall is intact with no evidence of a hernia. Surgisis can be successfully used for the reconstruction of complex abdominal wall defects in the pediatric patient, including reconstruction after separation of conjoined twins.

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Year:  2007        PMID: 17437118     DOI: 10.1007/s00383-007-1909-7

Source DB:  PubMed          Journal:  Pediatr Surg Int        ISSN: 0179-0358            Impact factor:   1.827


  21 in total

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Journal:  J Pediatr Surg       Date:  1998-05       Impact factor: 2.545

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Journal:  J Pediatr Surg       Date:  1998-05       Impact factor: 2.545

6.  Vascular endothelial growth factor in porcine-derived extracellular matrix.

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8.  Strength over time of a resorbable bioscaffold for body wall repair in a dog model.

Authors:  S Badylak; K Kokini; B Tullius; B Whitson
Journal:  J Surg Res       Date:  2001-08       Impact factor: 2.192

9.  Preliminary experience with new bioactive prosthetic material for repair of hernias in infected fields.

Authors:  M E Franklin; J J Gonzalez; R P Michaelson; J L Glass; D A Chock
Journal:  Hernia       Date:  2002-10-19       Impact factor: 4.739

10.  Clinical application of porcine small intestinal submucosa in the management of infected or potentially contaminated abdominal defects.

Authors:  Tomio Ueno; Lisa Clark Pickett; Sebastian G de la Fuente; D Curtis Lawson; Theodore N Pappas
Journal:  J Gastrointest Surg       Date:  2004-01       Impact factor: 3.452

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  4 in total

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2.  Porcine dermal collagen (Permacol) for chest and abdominal wall reconstruction in thoraco-omphalopagus conjoined twin separation.

Authors:  Jonathan Saul Karpelowsky; Alastair J W Millar
Journal:  Pediatr Surg Int       Date:  2009-10-10       Impact factor: 1.827

3.  Effectiveness and properties of the biological prosthesis Permacol™ in pediatric surgery: A large single center experience.

Authors:  Claudia Filisetti; Sara Costanzo; Federica Marinoni; Claudio Vella; Catherine Klercy; Giovanna Riccipetitoni
Journal:  Ann Med Surg (Lond)       Date:  2016-03-11

4.  Soft Tissue Repair with Easy-Accessible Autologous Newborn Placenta or Umbilical Cord Blood in Severe Malformations: A Primary Evaluation.

Authors:  Åsa Ekblad; Magdalena Fossum; Cecilia Götherström
Journal:  Stem Cells Int       Date:  2017-12-17       Impact factor: 5.443

  4 in total

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