Literature DB >> 1743508

A split zinc-finger protein is required for normal yeast growth.

H Blumberg1, P Silver.   

Abstract

We have identified a gene that, when present in multiple copies, partially inhibits nuclear protein localization in Saccharomyces cerevisiae. This gene encodes a protein that is a unique member of the Cys2His2 zinc-finger family of DNA-binding proteins. It is designated SFP1 for split finger protein because its two zinc-finger domains are separated from one another by 40 amino acids (aa) as opposed to the usual spacing of 7 or 8 aa for Cys2His2 proteins. Disruption of the SFP1 gene results in slow cell growth, with cells having multiple, nucleated buds.

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Year:  1991        PMID： 1743508     DOI： 10.1016/0378-1119(91)90302-r

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  14 in total

1.  Abnormal turning behavior in Drosophila larvae. Identification and molecular analysis of scribbler (sbb).

Authors:  P Yang; S A Shaver; A J Hilliker; M B Sokolowski
Journal:  Genetics       Date:  2000-07       Impact factor: 4.562

2.  Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression.

Authors:  Rosa M Marion; Aviv Regev; Eran Segal; Yoseph Barash; Daphne Koller; Nir Friedman; Erin K O'Shea
Journal:  Proc Natl Acad Sci U S A       Date:  2004-09-07       Impact factor: 11.205

3.  Compilation of sequence-specific DNA-binding proteins implicated in transcriptional control in fungi.

Authors:  S S Dhawale; A C Lane
Journal:  Nucleic Acids Res       Date:  1993-12-11       Impact factor: 16.971

4.  A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae.

Authors:  L Ni; M Snyder
Journal:  Mol Biol Cell       Date:  2001-07       Impact factor: 4.138

5.  Non-Mendelian determinant [ISP+] in yeast is a nuclear-residing prion form of the global transcriptional regulator Sfp1.

Authors:  Tatyana Rogoza; Alexander Goginashvili; Sofia Rodionova; Maxim Ivanov; Olga Viktorovskaya; Alexander Rubel; Kirill Volkov; Ludmila Mironova
Journal:  Proc Natl Acad Sci U S A       Date:  2010-05-24       Impact factor: 11.205

6.  The transcription factor Gcr1 stimulates cell growth by participating in nutrient-responsive gene expression on a global level.

Authors:  Kellie E Barbara; Terry M Haley; Kristine A Willis; George M Santangelo
Journal:  Mol Genet Genomics       Date:  2006-11-24       Impact factor: 3.291

7.  Discovery, validation, and genetic dissection of transcription factor binding sites by comparative and functional genomics.

Authors:  Jason Gertz; Linda Riles; Peter Turnbaugh; Su-Wen Ho; Barak A Cohen
Journal:  Genome Res       Date:  2005-08       Impact factor: 9.043

8.  Sfp1 plays a key role in yeast ribosome biogenesis.

Authors:  Ian Fingerman; Vijayalakshmi Nagaraj; David Norris; Andrew K Vershon
Journal:  Eukaryot Cell       Date:  2003-10

9.  The SFP1 gene product of Saccharomyces cerevisiae regulates G2/M transitions during the mitotic cell cycle and DNA-damage response.

Authors:  Z Xu; D Norris
Journal:  Genetics       Date:  1998-12       Impact factor: 4.562

10.  The yeast BDF1 gene encodes a transcription factor involved in the expression of a broad class of genes including snRNAs.

Authors:  Z Lygerou; C Conesa; P Lesage; R N Swanson; A Ruet; M Carlson; A Sentenac; B Séraphin
Journal:  Nucleic Acids Res       Date:  1994-12-11       Impact factor: 16.971
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