Literature DB >> 17434189

alpha-Glucosidase inhibitory constituents from stem bark of Terminalia superba (Combretaceae).

Jean Duplex Wansi1, Marie-Christine Lallemand, David Daco Chiozem, Flavien Aristide A Toze, Luc Meva'a Mbaze, Shamsun Naharkhan, Muhammad Choudhary Iqbal, François Tillequin, Jean Wandji, Zacharias Tanee Fomum.   

Abstract

The CH(2)Cl(2)/CH(3)OH (1/1) extract of the dried stem bark of Terminalia superba afforded two compounds, (7S,8R,7'R,8'S)-4'-hydroxy-4-methoxy-7,7'-epoxylignan and meso-(rel 7S,8R,7'R,8'S)-4,4'-dimethoxy-7,7'-epoxylignan along with 11 known compounds. The structures of the compounds were established by analysing the spectroscopic data and also comparing it with the data of previously known analogues. All the isolated compounds were evaluated for their glycosidase inhibition activities. Gallic acid and methyl gallate showed significant alpha-glucosidase inhibition activity.

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Year:  2007        PMID: 17434189     DOI: 10.1016/j.phytochem.2007.02.020

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  10 in total

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Journal:  J Am Soc Mass Spectrom       Date:  2009-04-14       Impact factor: 3.109

2.  Relationship Between Metabolites Composition and Biological Activities of Phyllanthus niruri Extracts Prepared by Different Drying Methods and Solvents Extraction.

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Review 3.  Plant-derived triterpenoids and analogues as antitumor and anti-HIV agents.

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Journal:  Nat Prod Rep       Date:  2009-08-13       Impact factor: 13.423

4.  α-glucosidase inhibitors from plants: A natural approach to treat diabetes.

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Journal:  Pharmacogn Rev       Date:  2011-01

5.  Characterization of Metabolite Profile in Phyllanthus niruri and Correlation with Bioactivity Elucidated by Nuclear Magnetic Resonance Based Metabolomics.

Authors:  Ahmed Mediani; Faridah Abas; M Maulidiani; Alfi Khatib; Chin Ping Tan; Intan Safinar Ismail; Khozirah Shaari; Amin Ismail
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Review 6.  The Genus Terminalia (Combretaceae): An Ethnopharmacological, Phytochemical and Pharmacological Review.

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Journal:  Nat Prod Bioprospect       Date:  2019-11-06

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8.  Investigation of Enzyme Inhibitory Activities, Antioxidant Activities, and Chemical Properties of Pistacia vera Leaves Using LC-QTOF-MS and RP-HPLC.

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9.  Identification of Digestive Enzyme Inhibitors from Ludwigia octovalvis (Jacq.) P.H.Raven.

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Journal:  Evid Based Complement Alternat Med       Date:  2018-07-16       Impact factor: 2.629

10.  Synthesis and α-Glucosidase Inhibition Activity of 2-[3-(Benzoyl/4-bromobenzoyl)-4-hydroxy-1,1-dioxido-2H-benzo[e][1,2]thiazin-2-yl]-N-arylacetamides: An In Silico and Biochemical Approach.

Authors:  Furqan Ahmad Saddique; Sana Aslam; Matloob Ahmad; Usman Ali Ashfaq; Muhammad Muddassar; Sadia Sultan; Saman Taj; Muzammil Hussain; Dae Sung Lee; Magdi E A Zaki
Journal:  Molecules       Date:  2021-05-20       Impact factor: 4.411

  10 in total

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