| Literature DB >> 17434043 |
Gregory J Fulchiero1, Heather Salvaggio, Joseph J Drabick, Kevin Staveley-O'Carroll, Elizabeth M Billingsley, James G Marks, Klaus F Helm.
Abstract
We report two cases of late recurrence of eruptive locoregional metastatic melanoma occurring 6 and 9 years after definitive surgical treatment. Each case (stage IB and IA) occurred after initiation of the subcutaneous anti-tumor necrosis factor medications etanercept and adalimumab, respectively. We discuss the association of immune suppression and melanoma. These cases illustrate a previously unrecognized and potentially causal relationship between tumor necrosis factor-alpha inhibition and reactivation of latent melanoma.Entities:
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Year: 2007 PMID: 17434043 DOI: 10.1016/j.jaad.2006.12.024
Source DB: PubMed Journal: J Am Acad Dermatol ISSN: 0190-9622 Impact factor: 11.527