Effect of aberrations and scatter on image resolution assessed by adaptive optics retinal section imaging.

The effect of increased high-order wavefront aberrations on image resolution was investigated, and the performance of adaptive optics (AO) for correcting wavefront error in the presence of increased light scatter was assessed in a model eye. An AO section imaging system provided an oblique view of a model retina and incorporated a wavefront sensor and deformable mirror for measurement and compensation of wavefront aberrations. Image resolution was quantified by the width of a Lorentzian curve fitted to a laser line image. Wavefront aberrations were significantly reduced with AO, resulting in improvement of image resolution. In the model eye, image resolution was degraded with increased high-order wavefront aberrations (horizontal coma and spherical) and improved with AO correction of wavefront error in the presence of increased light scatter. The findings of the current study suggest that AO imaging systems can potentially improve image resolution in aging eyes with increased aberrations and scatter.