| Literature DB >> 1742894 |
M Miyaguchi1, J Olofsson, H B Hellquist.
Abstract
The expression of EGFR was determined immunohistochemically in two groups of patients with glottic carcinoma, one that recurred after a full course of radiotherapy and one that did not. Using a 4-graded scale (-,+,++, ) 80% (12/15) of the recurrent carcinomas had a staining intensity and proportion of stained cells of ++ or more. The same figure for non-recurrent carcinomas was 39% (7/18). The difference is statistically significant (chi-squared with Yates' correction, P less than 0.05). The results indicate that an increased expression of EGFR may influence the rate of recurrence of glottic squamous cell carcinoma after radiotherapy.Entities:
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Year: 1991 PMID： 1742894 DOI： 10.1111/j.1365-2273.1991.tb01041.x
Source DB: PubMed Journal: Clin Otolaryngol Allied Sci ISSN： 0307-7772