Literature DB >> 17426819

Mature Homogeneous Erythropoietin-Level Building Blocks by Chemical Synthesis: The EPO 114-166 Glycopeptide Domain, Presenting the O-Linked Glycophorin.

Jiehao Chen1, Gong Chen, Bin Wu, Qian Wan, Zhongping Tan, Zihao Hua, Samuel J Danishefsky.   

Abstract

A synthesis of EPO 114-166 glycopeptide (1), presenting the O-linked glycophorin of erythropoietin, is described.

Entities:  

Year:  2006        PMID: 17426819      PMCID: PMC1849969          DOI: 10.1016/j.tetlet.2006.09.045

Source DB:  PubMed          Journal:  Tetrahedron Lett        ISSN: 0040-4039            Impact factor:   2.415


  11 in total

1.  Extending synthetic access to proteins with a removable acyl transfer auxiliary.

Authors:  John Offer; C N C Boddy; Philip E Dawson
Journal:  J Am Chem Soc       Date:  2002-05-01       Impact factor: 15.419

2.  Toward fully synthetic glycoproteins by ultimately convergent routes: a solution to a long-standing problem.

Authors:  J David Warren; Justin S Miller; Stacy J Keding; Samuel J Danishefsky
Journal:  J Am Chem Soc       Date:  2004-06-02       Impact factor: 15.419

3.  Studies related to the relative thermodynamic stability of C-terminal peptidyl esters of O-hydroxy thiophenol: emergence of a doable strategy for non-cysteine ligation applicable to the chemical synthesis of glycopeptides.

Authors:  Gong Chen; J David Warren; Jiehao Chen; Bin Wu; Qian Wan; Samuel J Danishefsky
Journal:  J Am Chem Soc       Date:  2006-06-14       Impact factor: 15.419

4.  Building complex glycopeptides: Development of a cysteine-free native chemical ligation protocol.

Authors:  Bin Wu; Jiehao Chen; J David Warren; Gong Chen; Zihao Hua; Samuel J Danishefsky
Journal:  Angew Chem Int Ed Engl       Date:  2006-06-19       Impact factor: 15.336

5.  3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one (DEPBT): a new coupling reagent with remarkable resistance to racemization.

Authors:  H Li; X Jiang; Y H Ye; C Fan; T Romoff; M Goodman
Journal:  Org Lett       Date:  1999-07-15       Impact factor: 6.005

Review 6.  Synthesis of large peptides in solution.

Authors:  S Sakakibara
Journal:  Biopolymers       Date:  1995       Impact factor: 2.505

7.  Synthesis of peptides and proteins without cysteine residues by native chemical ligation combined with desulfurization.

Authors:  L Z Yan; P E Dawson
Journal:  J Am Chem Soc       Date:  2001-01-31       Impact factor: 15.419

8.  Nalpha-2-mercaptobenzylamine-assisted chemical ligation.

Authors:  J Offer; P E Dawson
Journal:  Org Lett       Date:  2000-01       Impact factor: 6.005

9.  Powerful solvent systems useful for synthesis of sparingly-soluble peptides in solution.

Authors:  H Kuroda; Y N Chen; T Kimura; S Sakakibara
Journal:  Int J Pept Protein Res       Date:  1992 Sep-Oct

10.  Structural characterization of human erythropoietin.

Authors:  P H Lai; R Everett; F F Wang; T Arakawa; E Goldwasser
Journal:  J Biol Chem       Date:  1986-03-05       Impact factor: 5.157

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  10 in total

1.  Insights into the finer issues of native chemical ligation: an approach to cascade ligations.

Authors:  Zhongping Tan; Shiying Shang; Samuel J Danishefsky
Journal:  Angew Chem Int Ed Engl       Date:  2010-12-03       Impact factor: 15.336

2.  Toward homogeneous erythropoietin: fine tuning of the C-terminal acyl donor in the chemical synthesis of the Cys29-Gly77 glycopeptide domain.

Authors:  Yu Yuan; Jin Chen; Qian Wan; Zhongping Tan; Gong Chen; Cindy Kan; Samuel J Danishefsky
Journal:  J Am Chem Soc       Date:  2009-04-22       Impact factor: 15.419

3.  Recent Departures in the Synthesis of Peptides and Glycopeptides.

Authors:  Cindy Kan; Samuel J Danishefsky
Journal:  Tetrahedron       Date:  2009-11-07       Impact factor: 2.457

4.  Total synthesis of the 2,6-sialylated immunoglobulin G glycopeptide fragment in homogeneous form.

Authors:  Ping Wang; Jianglong Zhu; Yu Yuan; Samuel J Danishefsky
Journal:  J Am Chem Soc       Date:  2009-11-25       Impact factor: 15.419

5.  Sugar-assisted glycopeptide ligation with complex oligosaccharides: scope and limitations.

Authors:  Clay S Bennett; Stephen M Dean; Richard J Payne; Simon Ficht; Ashraf Brik; Chi-Huey Wong
Journal:  J Am Chem Soc       Date:  2008-08-13       Impact factor: 15.419

Review 6.  The winding pathway to erythropoietin along the chemistry-biology frontier: a success at last.

Authors:  Rebecca M Wilson; Suwei Dong; Ping Wang; Samuel J Danishefsky
Journal:  Angew Chem Int Ed Engl       Date:  2013-06-17       Impact factor: 15.336

7.  Sugar-assisted ligation in glycoprotein synthesis.

Authors:  Yu-Ying Yang; Simon Ficht; Ashraf Brik; Chi-Huey Wong
Journal:  J Am Chem Soc       Date:  2007-05-25       Impact factor: 15.419

8.  Mature Homogeneous Erythropoietin-Level Building Blocks by Chemical Synthesis: The EPO 114-166 Glycopeptide Domain, Presenting the O-Linked Glycophorin.

Authors:  Jiehao Chen; Gong Chen; Bin Wu; Qian Wan; Zhongping Tan; Zihao Hua; Samuel J Danishefsky
Journal:  Tetrahedron Lett       Date:  2006-11-13       Impact factor: 2.415

9.  Toward homogeneous erythropoietin: non-NCL-based chemical synthesis of the Gln78-Arg166 glycopeptide domain.

Authors:  Zhongping Tan; Shiying Shang; Tamara Halkina; Yu Yuan; Samuel J Danishefsky
Journal:  J Am Chem Soc       Date:  2009-04-22       Impact factor: 15.419

10.  Toward homogeneous erythropoietin: chemical synthesis of the Ala1-Gly28 glycopeptide domain by "alanine" ligation.

Authors:  Cindy Kan; John D Trzupek; Bin Wu; Qian Wan; Gong Chen; Zhongping Tan; Yu Yuan; Samuel J Danishefsky
Journal:  J Am Chem Soc       Date:  2009-04-22       Impact factor: 15.419

  10 in total

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