Literature DB >> 17425920

The search for type 2 diabetes susceptibility loci: the chromosome 1q story.

Swapan Kumar Das1, Steven C Elbein.   

Abstract

The unbiased approach of genome-wide linkage analysis has shown evidence for linkage of type 2 diabetes mellitus to the chromosome 1q21-25 region in at least eight independent studies. More than 26 candidate genes have already been evaluated, but to date none explain the evidence for linkage in this gene-dense region. Considerable data suggest that multiple genes account for this linkage result. The search for these genes is now the focus of an international consortium of groups reporting linkage of type 2 diabetes to this region of chromosome 1q21-q25.

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Year:  2007        PMID： 17425920     DOI： 10.1007/s11892-007-0025-3

Source DB:  PubMed          Journal:  Curr Diab Rep        ISSN： 1534-4827            Impact factor:   5.430


  49 in total

1.  Analysis of linkage disequilibrium between polymorphisms in the KCNJ9 gene with type 2 diabetes mellitus in Pima Indians.

Authors:  J K Wolford; R L Hanson; S Kobes; C Bogardus; M Prochazka
Journal:  Mol Genet Metab       Date:  2001-05       Impact factor: 4.797

2.  Linkage and association mapping of a chromosome 1q21-q24 type 2 diabetes susceptibility locus in northern European Caucasians.

Authors:  Swapan Kumar Das; Sandra J Hasstedt; Zhengxian Zhang; Steven C Elbein
Journal:  Diabetes       Date:  2004-02       Impact factor: 9.461

3.  Analysis of the lamin A/C gene as a candidate for type II diabetes susceptibility in Pima Indians.

Authors:  J K Wolford; R L Hanson; C Bogardus; M Prochazka
Journal:  Diabetologia       Date:  2001-06       Impact factor: 10.122

4.  Molecular analysis of KCNJ10 on 1q as a candidate gene for Type 2 diabetes in Pima Indians.

Authors:  Vidya S Farook; Robert L Hanson; Johanna K Wolford; Clifton Bogardus; Michal Prochazka
Journal:  Diabetes       Date:  2002-11       Impact factor: 9.461

5.  Polymorphism screening of the insulin receptor-related receptor gene (INSRR) on 1q in Pima Indians.

Authors:  J K Wolford; F Thameem; C Bogardus; M Prochazka
Journal:  Mol Cell Probes       Date:  2001-08       Impact factor: 2.365

6.  Polymorphism in the calsequestrin 1 (CASQ1) gene on chromosome 1q21 is associated with type 2 diabetes in the old order Amish.

Authors:  Mao Fu; Coleen M Damcott; Mona Sabra; Toni I Pollin; Sandra H Ott; Jian Wang; Michael J Garant; Jeffrey R O'Connell; Braxton D Mitchell; Alan R Shuldiner
Journal:  Diabetes       Date:  2004-12       Impact factor: 9.461

7.  Variation in the interleukin-6 receptor gene associates with type 2 diabetes in Danish whites.

Authors:  Yasmin H Hamid; Søren A Urhammer; Dorit P Jensen; Charlotte Glümer; Knut Borch-Johnsen; Torben Jørgensen; Torben Hansen; Oluf Pedersen
Journal:  Diabetes       Date:  2004-12       Impact factor: 9.461

8.  Genome-wide scan for metabolic syndrome and related quantitative traits in Hong Kong Chinese and confirmation of a susceptibility locus on chromosome 1q21-q25.

Authors:  Maggie C Y Ng; Wing-Yee So; Vincent K L Lam; Clive S Cockram; Graeme I Bell; Nancy J Cox; Juliana C N Chan
Journal:  Diabetes       Date:  2004-10       Impact factor: 9.461

9.  Association of a F479L variant in the cytosolic phospholipase A2 gene (PLA2G4A) with decreased glucose turnover and oxidation rates in Pima Indians.

Authors:  Johanna K Wolford; Yasmine L Konheim; Peter B Colligan; Clifton Bogardus
Journal:  Mol Genet Metab       Date:  2003-05       Impact factor: 4.797

10.  The DNA sequence and biological annotation of human chromosome 1.

Authors:  S G Gregory; K F Barlow; K E McLay; R Kaul; D Swarbreck; A Dunham; C E Scott; K L Howe; K Woodfine; C C A Spencer; M C Jones; C Gillson; S Searle; Y Zhou; F Kokocinski; L McDonald; R Evans; K Phillips; A Atkinson; R Cooper; C Jones; R E Hall; T D Andrews; C Lloyd; R Ainscough; J P Almeida; K D Ambrose; F Anderson; R W Andrew; R I S Ashwell; K Aubin; A K Babbage; C L Bagguley; J Bailey; H Beasley; G Bethel; C P Bird; S Bray-Allen; J Y Brown; A J Brown; D Buckley; J Burton; J Bye; C Carder; J C Chapman; S Y Clark; G Clarke; C Clee; V Cobley; R E Collier; N Corby; G J Coville; J Davies; R Deadman; M Dunn; M Earthrowl; A G Ellington; H Errington; A Frankish; J Frankland; L French; P Garner; J Garnett; L Gay; M R J Ghori; R Gibson; L M Gilby; W Gillett; R J Glithero; D V Grafham; C Griffiths; S Griffiths-Jones; R Grocock; S Hammond; E S I Harrison; E Hart; E Haugen; P D Heath; S Holmes; K Holt; P J Howden; A R Hunt; S E Hunt; G Hunter; J Isherwood; R James; C Johnson; D Johnson; A Joy; M Kay; J K Kershaw; M Kibukawa; A M Kimberley; A King; A J Knights; H Lad; G Laird; S Lawlor; D A Leongamornlert; D M Lloyd; J Loveland; J Lovell; M J Lush; R Lyne; S Martin; M Mashreghi-Mohammadi; L Matthews; N S W Matthews; S McLaren; S Milne; S Mistry; M J F Moore; T Nickerson; C N O'Dell; K Oliver; A Palmeiri; S A Palmer; A Parker; D Patel; A V Pearce; A I Peck; S Pelan; K Phelps; B J Phillimore; R Plumb; J Rajan; C Raymond; G Rouse; C Saenphimmachak; H K Sehra; E Sheridan; R Shownkeen; S Sims; C D Skuce; M Smith; C Steward; S Subramanian; N Sycamore; A Tracey; A Tromans; Z Van Helmond; M Wall; J M Wallis; S White; S L Whitehead; J E Wilkinson; D L Willey; H Williams; L Wilming; P W Wray; Z Wu; A Coulson; M Vaudin; J E Sulston; R Durbin; T Hubbard; R Wooster; I Dunham; N P Carter; G McVean; M T Ross; J Harrow; M V Olson; S Beck; J Rogers; D R Bentley; R Banerjee; S P Bryant; D C Burford; W D H Burrill; S M Clegg; P Dhami; O Dovey; L M Faulkner; S M Gribble; C F Langford; R D Pandian; K M Porter; E Prigmore
Journal:  Nature       Date:  2006-05-18       Impact factor: 49.962
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  24 in total

1.  Replication in genome-wide association studies.

Authors:  Peter Kraft; Eleftheria Zeggini; John P A Ioannidis
Journal:  Stat Sci       Date:  2009-11-01       Impact factor: 2.901

2.  Genetic analysis of atherosclerosis and glucose homeostasis in an intercross between C57BL/6 and BALB/cJ apolipoprotein E-deficient mice.

Authors:  Zhimin Zhang; Jessica S Rowlan; Qian Wang; Weibin Shi
Journal:  Circ Cardiovasc Genet       Date:  2012-01-31

Review 3.  Genetics factors contributing to type 2 diabetes across ethnicities.

Authors:  Steven C Elbein
Journal:  J Diabetes Sci Technol       Date:  2009-07-01

4.  Tissue-Specific and Genetic Regulation of Insulin Sensitivity-Associated Transcripts in African Americans.

Authors:  Neeraj K Sharma; Satria P Sajuthi; Jeff W Chou; Jorge Calles-Escandon; Jamehl Demons; Samantha Rogers; Lijun Ma; Nicholette D Palmer; David R McWilliams; John Beal; Mary E Comeau; Kristina Cherry; Gregory A Hawkins; Lata Menon; Ethel Kouba; Donna Davis; Marcie Burris; Sara J Byerly; Linda Easter; Donald W Bowden; Barry I Freedman; Carl D Langefeld; Swapan K Das
Journal:  J Clin Endocrinol Metab       Date:  2016-01-20       Impact factor: 5.958

5.  Phenotypic and molecular evaluation of a chromosome 1q region with linkage and association to type 2 diabetes in humans.

Authors:  Hua Wang; Nicholas P Hays; Swapan K Das; Rebekah L Craig; Winston S Chu; Neeraj Sharma; Steven C Elbein
Journal:  J Clin Endocrinol Metab       Date:  2009-01-13       Impact factor: 5.958

6.  Significant association between body composition phenotypes and the osteocalcin genomic region in normative human population.

Authors:  Michael Korostishevsky; Ida Malkin; Svetlana Trofimov; Yufang Pei; Hong-Wen Deng; Gregory Livshits
Journal:  Bone       Date:  2012-07-24       Impact factor: 4.398

7.  Genome-wide linkage scan for factors of metabolic syndrome in a Chinese population.

Authors:  Claudia H T Tam; Vincent K L Lam; Wing-Yee So; Ronald C W Ma; Juliana C N Chan; Maggie C Y Ng
Journal:  BMC Genet       Date:  2010-02-24       Impact factor: 2.797

8.  Allelic expression imbalance screening of genes in chromosome 1q21-24 region to identify functional variants for Type 2 diabetes susceptibility.

Authors:  Ashis K Mondal; Neeraj K Sharma; Steven C Elbein; Swapan K Das
Journal:  Physiol Genomics       Date:  2013-05-14       Impact factor: 3.107

Review 9.  Expression quantitative trait analyses to identify causal genetic variants for type 2 diabetes susceptibility.

Authors:  Swapan Kumar Das; Neeraj Kumar Sharma
Journal:  World J Diabetes       Date:  2014-04-15

Review 10.  Psoriasis and metabolic disease: epidemiology and pathophysiology.

Authors:  Rahat S Azfar; Joel M Gelfand
Journal:  Curr Opin Rheumatol       Date:  2008-07       Impact factor: 5.006
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