Literature DB >> 17420567

A new nucleosidyl-peptide antibiotic, sansanmycin.

Yunying Xie1, Ruxian Chen, Shuyi Si, Chenghang Sun, Hongzhang Xu.   

Abstract

A new nucleosidyl-peptide antibiotic, sansanmycin, was isolated from an unidentified Streptomyces sp SS. The structure of sansanmycin was elucidated by analyses of its alkaline hydrolysate and spectroscopic analyses. Sansanmycin exhibits antibacterial activity against Mycobacterium tuberculosis H(37)Ra and Pseudomonas aeruginosa with MIC values of 10 and 12.5 mug/ml, respectively.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17420567     DOI： 10.1038/ja.2007.16

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  13 in total

Review 1.  New antituberculous drugs derived from natural products: current perspectives and issues in antituberculous drug development.

Authors:  Masayuki Igarashi; Yoshimasa Ishizaki; Yoshiaki Takahashi
Journal:  J Antibiot (Tokyo)       Date:  2017-11-01       Impact factor: 2.649

2.  Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics.

Authors:  Wenjun Zhang; Ioanna Ntai; Megan L Bolla; Steven J Malcolmson; Daniel Kahne; Neil L Kelleher; Christopher T Walsh
Journal:  J Am Chem Soc       Date:  2011-03-18       Impact factor: 15.419

Review 3.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

4.  Precursor-directed biosynthesis of new sansanmycin analogs bearing para-substituted-phenylalanines with high yields.

Authors:  Ningning Zhang; Li Liu; Guangzhi Shan; Qiang Cai; Xuan Lei; Bin Hong; Linzhuan Wu; Yunying Xie; Ruxian Chen
Journal:  J Antibiot (Tokyo)       Date:  2016-02-24       Impact factor: 2.649

5.  The quest for supernatural products: the impact of total synthesis in complex natural products medicinal chemistry.

Authors:  Zhi-Chen Wu; Dale L Boger
Journal:  Nat Prod Rep       Date:  2020-11-10       Impact factor: 13.423

6.  SsaA, a member of a novel class of transcriptional regulators, controls sansanmycin production in Streptomyces sp. strain SS through a feedback mechanism.

Authors:  Qinglian Li; Lifei Wang; Yunying Xie; Songmei Wang; Ruxian Chen; Bin Hong
Journal:  J Bacteriol       Date:  2013-03-08       Impact factor: 3.490

7.  Draft genome sequence of Streptomyces sp. strain SS, which produces a series of uridyl peptide antibiotic sansanmycins.

Authors:  Lifei Wang; Yunying Xie; Qinglian Li; Ning He; Entai Yao; Hongzhang Xu; Ying Yu; Ruxian Chen; Bin Hong
Journal:  J Bacteriol       Date:  2012-12       Impact factor: 3.490

Review 8.  Identification and characterization of enzymes involved in the biosynthesis of pyrimidine nucleoside antibiotics.

Authors:  M McErlean; X Liu; Z Cui; B Gust; S G Van Lanen
Journal:  Nat Prod Rep       Date:  2021-07-21       Impact factor: 15.111

9.  Identification of novel mureidomycin analogues via rational activation of a cryptic gene cluster in Streptomyces roseosporus NRRL 15998.

Authors:  Lingjuan Jiang; Lu Wang; Jihui Zhang; Hao Liu; Bin Hong; Huarong Tan; Guoqing Niu
Journal:  Sci Rep       Date:  2015-09-15       Impact factor: 4.379

10.  Improving the N-terminal diversity of sansanmycin through mutasynthesis.

Authors:  Yuanyuan Shi; Zhibo Jiang; Xuan Lei; Ningning Zhang; Qiang Cai; Qinglian Li; Lifei Wang; Shuyi Si; Yunying Xie; Bin Hong
Journal:  Microb Cell Fact       Date:  2016-05-06       Impact factor: 5.328
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.