OBJECTIVE: To describe the use of a single donor corneal tissue in 3 patients with corneal pathologic conditions. METHODS: A donor corneal tissue was divided into 3 parts using a microkeratome and a trephine. The anterior lamellar disc was transplanted into a patient with macular corneal dystrophy using the automated lamellar therapeutic keratoplasty technique. The posterior lamellar disc was transplanted into a patient with pseudophakic bullous keratopathy using the Descemet stripping automated endothelial keratoplasty technique. The peripheral corneoscleral rim was used for limbal stem cell transplantation in a child with limbal stem cell deficiency. RESULTS: All surgical procedures were performed successfully. At 3 months, the best-corrected visual acuities achieved following automated lamellar therapeutic keratoplasty, Descemet stripping automated endothelial keratoplasty, and limbal stem cell transplantation were 20/60, 20/40, and 20/200, respectively. CONCLUSION: The advent of customized component corneal transplantation techniques may allow the use of 1 donor cornea to treat multiple patients.
OBJECTIVE: To describe the use of a single donor corneal tissue in 3 patients with corneal pathologic conditions. METHODS: A donor corneal tissue was divided into 3 parts using a microkeratome and a trephine. The anterior lamellar disc was transplanted into a patient with macular corneal dystrophy using the automated lamellar therapeutic keratoplasty technique. The posterior lamellar disc was transplanted into a patient with pseudophakic bullous keratopathy using the Descemet stripping automated endothelial keratoplasty technique. The peripheral corneoscleral rim was used for limbal stem cell transplantation in a child with limbal stem cell deficiency. RESULTS: All surgical procedures were performed successfully. At 3 months, the best-corrected visual acuities achieved following automated lamellar therapeutic keratoplasty, Descemet stripping automated endothelial keratoplasty, and limbal stem cell transplantation were 20/60, 20/40, and 20/200, respectively. CONCLUSION: The advent of customized component corneal transplantation techniques may allow the use of 1 donor cornea to treat multiple patients.
Authors: Tien-En Tan; Gary S L Peh; Benjamin L George; Howard Y Cajucom-Uy; Di Dong; Eric A Finkelstein; Jodhbir S Mehta Journal: PLoS One Date: 2014-06-20 Impact factor: 3.240