Literature DB >> 17418830

Korean ginseng induces spermatogenesis in rats through the activation of cAMP-responsive element modulator (CREM).

Wan Su Park1, Dong Youp Shin, Do Rim Kim, Woong Mo Yang, Mun Seog Chang, Seong Kyu Park.   

Abstract

The effect of Korean ginseng (ginseng) on spermatogenesis and cAMP-responsive element modulator (CREM) in rat testes was evaluated using sperm analysis, reverse transcription polymerase chain reaction, and Western blot analysis. The ginseng-treated rats exhibited significantly increased sperm count and motility with enhanced levels of CREM messenger RNA and protein. Ginseng appears to induce spermatogenesis via CREM activation in rat testes.

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Year:  2007        PMID： 17418830     DOI： 10.1016/j.fertnstert.2006.12.014

Source DB:  PubMed          Journal:  Fertil Steril        ISSN： 0015-0282            Impact factor:   7.329


  14 in total

1.  Effects of Korean red ginseng on semen parameters in male infertility patients: A randomized, placebo-controlled, double-blind clinical study.

Authors:  Hyun Jun Park; Sangmin Choe; Nam Cheol Park
Journal:  Chin J Integr Med       Date:  2015-05-12       Impact factor: 1.978

Review 2.  Rise of herbal and traditional medicine in erectile dysfunction management.

Authors:  Christopher C K Ho; Hui Meng Tan
Journal:  Curr Urol Rep       Date:  2011-12       Impact factor: 3.092

Review 3.  Phytomedicinal therapeutics for male infertility: critical insights and scientific updates.

Authors:  Shalaka S Ramgir; Kaviyarasi Renu; Balachandar Vellingiri; Alex George; Damodaran Tirupapuliyur; Padma Thiagarajan; Abilash Valsala Gopalakrishnan
Journal:  J Nat Med       Date:  2022-04-04       Impact factor: 2.343

4.  Stereological study of the effect of ginger's alcoholic extract on the testis in busulfan-induced infertility in rats.

Authors:  Hossein Bordbar; Tahereh Esmaeilpour; Farzaneh Dehghani; Mohammad Reza Panjehshahin
Journal:  Iran J Reprod Med       Date:  2013-06

Review 5.  Ginseng and male reproductive function.

Authors:  Kar Wah Leung; Alice St Wong
Journal:  Spermatogenesis       Date:  2013-09-13

6.  Ameliorating Effect of Ginseng on Epididymo-Orchitis Inducing Alterations in Sperm Quality and Spermatogenic Cells Apoptosis following Infection by Uropathogenic Escherichia coli in Rats.

Authors:  Mehdi Eskandari; Soghra Jani; Mahsa Kazemi; Habib Zeighami; Alireza Yazdinezhad; Sahar Mazloomi; Saeed Shokri
Journal:  Cell J       Date:  2016-08-24       Impact factor: 2.479

7.  Astragalus membranaceus augment sperm parameters in male mice associated with cAMP-responsive element modulator and activator of CREM in testis.

Authors:  Wonnam Kim; Do Rim Kim; Mun Seog Chang; Seong Kyu Park
Journal:  J Tradit Complement Med       Date:  2015-11-07

8.  Enhanced inhibitory effect of ultra-fine granules of red ginseng on LPS-induced cytokine expression in the monocyte-derived macrophage THP-1 cells.

Authors:  Hyoung-Cheol Lee; Radhakrishnan Vinodhkumar; Jang W Yoon; Seong-Kyu Park; Chang-Won Lee; Hong-Yeoul Kim
Journal:  Int J Mol Sci       Date:  2008-08-07       Impact factor: 6.208

9.  Korean Red Ginseng Up-regulates C21-Steroid Hormone Metabolism via Cyp11a1 Gene in Senescent Rat Testes.

Authors:  In-Hye Kim; Si-Kwan Kim; Eun-Hye Kim; Sung-Won Kim; Sang-Hyun Sohn; Soo Cheol Lee; Sangdun Choi; Suhkneung Pyo; Dong-Kwon Rhee
Journal:  J Ginseng Res       Date:  2011-09       Impact factor: 6.060

10.  Panax ginseng induces the expression of CatSper genes and sperm hyperactivation.

Authors:  Eun Hwa Park; Do Rim Kim; Ha Young Kim; Seong Kyu Park; Mun Seog Chang
Journal:  Asian J Androl       Date:  2014 Nov-Dec       Impact factor: 3.285
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