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Literature DB >> 17413855

Assessment of infant brain development with frequency-domain near-infrared spectroscopy.

Maria Angela Franceschini¹, Sonal Thaker, George Themelis, Kalpathy K Krishnamoorthy, Heather Bortfeld, Solomon G Diamond, David A Boas, Kara Arvin, P Ellen Grant.

Abstract

This is the first report to demonstrate quantitative monitoring of infant brain development with frequency-domain near-infrared spectroscopy (FD-NIRS). Regionally specific increases in blood volume and oxygen consumption were measured in healthy infants during their first year. The results agree with prior PET and SPECT reports; but, unlike these methods, FD-NIRS is portable and uses nonionizing radiation. Further, new information includes the relatively constant tissue oxygenation with age and location, suggesting a tight control between local oxygen delivery and consumption in healthy infants during brain development. FD-NIRS could become the preferred clinical tool for quantitatively assessing infant brain development.

Entities: Chemical Species

Mesh：

Year: 2007 PMID： 17413855 PMCID： PMC2637818 DOI： 10.1203/pdr.0b013e318045be99

Source DB: PubMed Journal: Pediatr Res ISSN： 0031-3998 Impact factor: 3.756

32 in total

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