OBJECTIVE: To compare the effect of a honey dressing vs an ethoxy-diaminoacridine plus nitrofurazone dressing in patients with pressure ulcers. DESIGN: This 5-week randomized clinical trial evaluated the effect of a honey dressing on pressure ulcer healing. SETTING AND SUBJECTS:Thirty-six patients with a total of 68 stage II or III pressure ulcers referred from a university hospital in Izmir were enrolled in the study. Twenty-six subjects completed the trial. INSTRUMENTS: Ulcers were measured with acetate tracings and Pressure Ulcer Scale for Healing (PUSH) evaluations. METHODS:Fifteen patients with 25 pressure ulcers were treated with honey dressings, and 11 patients with 25 pressure ulcers were treated with ethoxy-diaminoacridine plus nitrofurazone dressings. Wound healing was assessed weekly using the PUSH tool, version 3.0. The primary outcome measure was the change in PUSH tool scores in each group at 5 weeks. RESULTS: The two groups were statistically similar with regard to baseline and wound characteristics. After 5 weeks of treatment, patients who were treated by honey dressing had significantly better PUSH tool scores than subjects treated with the ethoxy-diaminoacridine plus nitrofurazone dressing (6.55 +/- 2.14 vs 12.62 +/- 2.15, P < .001). CONCLUSION: By week 5, PUSH tool scores showed that healing among subjects using a honey dressing was approximately 4 times the rate of healing in the comparison group. The use of a honey dressing is effective and practical.
RCT Entities:
OBJECTIVE: To compare the effect of a honey dressing vs an ethoxy-diaminoacridine plus nitrofurazone dressing in patients with pressure ulcers. DESIGN: This 5-week randomized clinical trial evaluated the effect of a honey dressing on pressure ulcer healing. SETTING AND SUBJECTS: Thirty-six patients with a total of 68 stage II or III pressure ulcers referred from a university hospital in Izmir were enrolled in the study. Twenty-six subjects completed the trial. INSTRUMENTS: Ulcers were measured with acetate tracings and Pressure Ulcer Scale for Healing (PUSH) evaluations. METHODS: Fifteen patients with 25 pressure ulcers were treated with honey dressings, and 11 patients with 25 pressure ulcers were treated with ethoxy-diaminoacridine plus nitrofurazone dressings. Wound healing was assessed weekly using the PUSH tool, version 3.0. The primary outcome measure was the change in PUSH tool scores in each group at 5 weeks. RESULTS: The two groups were statistically similar with regard to baseline and wound characteristics. After 5 weeks of treatment, patients who were treated by honey dressing had significantly better PUSH tool scores than subjects treated with the ethoxy-diaminoacridine plus nitrofurazone dressing (6.55 +/- 2.14 vs 12.62 +/- 2.15, P < .001). CONCLUSION: By week 5, PUSH tool scores showed that healing among subjects using a honey dressing was approximately 4 times the rate of healing in the comparison group. The use of a honey dressing is effective and practical.
Authors: Bahram Biglari; Arash Moghaddam; Kai Santos; Gisela Blaser; Axel Büchler; Gisela Jansen; Alfred Längler; Norbert Graf; Ursula Weiler; Verena Licht; Anke Strölin; Brigitta Keck; Volker Lauf; Udo Bode; Tyler Swing; Ralph Hanano; Nicolas T Schwarz; Arne Simon Journal: Int Wound J Date: 2012-04-11 Impact factor: 3.315
Authors: Shannon E Fogh; Snehal Deshmukh; Lawrence B Berk; Amylou C Dueck; Kevin Roof; Sherif Yacoub; Thomas Gergel; Kevin Stephans; Andreas Rimner; Albert DeNittis; John Pablo; Justin Rineer; Terence M Williams; Deborah Bruner Journal: Int J Radiat Oncol Biol Phys Date: 2016-11-23 Impact factor: 7.038
Authors: Arne Simon; Kirsten Traynor; Kai Santos; Gisela Blaser; Udo Bode; Peter Molan Journal: Evid Based Complement Alternat Med Date: 2008-01-07 Impact factor: 2.629