| Literature DB >> 17411097 |
Yuguo Du1, Jun Liu, Robert J Linhardt.
Abstract
(+/-)-Paeonilide, a novel monoterpenoid metabolite from the roots of Paeonia delavayi showing anti-platelet activating factor activity, is convergently synthesized in five steps with 59% overall yield. The application of benzoyl peroxide-promoted radical addition of unsaturated ester to aldehyde and subsequent topologically favored cyclization greatly simplified the synthesis.Entities:
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Year: 2007 PMID： 17411097 PMCID： PMC4142627 DOI： 10.1021/jo0701278
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354