Literature DB >> 17408273

The acylation mechanism of CTX-M beta-lactamase at 0.88 a resolution.

Yu Chen1, Richard Bonnet, Brian K Shoichet.   

Abstract

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Year:  2007        PMID： 17408273      PMCID： PMC2577156          DOI： 10.1021/ja0712064

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


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  22 in total

1.  Atomic resolution structures of CTX-M beta-lactamases: extended spectrum activities from increased mobility and decreased stability.

Authors:  Yu Chen; Julien Delmas; Jacques Sirot; Brian Shoichet; Richard Bonnet
Journal:  J Mol Biol       Date:  2005-04-29       Impact factor: 5.469

2.  SHELXL: high-resolution refinement.

Authors:  G M Sheldrick; T R Schneider
Journal:  Methods Enzymol       Date:  1997       Impact factor: 1.600

3.  Ultrahigh resolution structure of a class A beta-lactamase: on the mechanism and specificity of the extended-spectrum SHV-2 enzyme.

Authors:  Michiyoshi Nukaga; Kayoko Mayama; Andrea M Hujer; Robert A Bonomo; James R Knox
Journal:  J Mol Biol       Date:  2003-04-18       Impact factor: 5.469

4.  Crystal structure of an acylation transition-state analog of the TEM-1 beta-lactamase. Mechanistic implications for class A beta-lactamases.

Authors:  L Maveyraud; R F Pratt; J P Samama
Journal:  Biochemistry       Date:  1998-02-24       Impact factor: 3.162

5.  The catalytic mechanism of beta-lactamases: NMR titration of an active-site lysine residue of the TEM-1 enzyme.

Authors:  C Damblon; X Raquet; L Y Lian; J Lamotte-Brasseur; E Fonze; P Charlier; G C Roberts; J M Frère
Journal:  Proc Natl Acad Sci U S A       Date:  1996-03-05       Impact factor: 11.205

6.  Ab initio QM/MM study of class A beta-lactamase acylation: dual participation of Glu166 and Lys73 in a concerted base promotion of Ser70.

Authors:  Samy O Meroueh; Jed F Fisher; H Bernhard Schlegel; Shahriar Mobashery
Journal:  J Am Chem Soc       Date:  2005-11-09       Impact factor: 15.419

7.  Mechanism of acyl transfer by the class A serine beta-lactamase of Streptomyces albus G.

Authors:  J Lamotte-Brasseur; G Dive; O Dideberg; P Charlier; J M Frère; J M Ghuysen
Journal:  Biochem J       Date:  1991-10-01       Impact factor: 3.857

8.  Site-directed mutagenesis of glutamate-166 in beta-lactamase leads to a branched path mechanism.

Authors:  W A Escobar; A K Tan; E R Lewis; A L Fink
Journal:  Biochemistry       Date:  1994-06-21       Impact factor: 3.162

9.  Crystal structure of the E166A mutant of extended-spectrum beta-lactamase Toho-1 at 1.8 A resolution.

Authors:  A Ibuka; A Taguchi; M Ishiguro; S Fushinobu; Y Ishii; S Kamitori; K Okuyama; K Yamaguchi; M Konno; H Matsuzawa
Journal:  J Mol Biol       Date:  1999-02-05       Impact factor: 5.469

10.  Protonation of the beta-lactam nitrogen is the trigger event in the catalytic action of class A beta-lactamases.

Authors:  B P Atanasov; D Mustafi; M W Makinen
Journal:  Proc Natl Acad Sci U S A       Date:  2000-03-28       Impact factor: 11.205
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  26 in total

1.  Noncovalent complexes of an inactive mutant of CTX-M-9 with the substrate piperacillin and the corresponding product.

Authors:  David Leyssene; Julien Delmas; Frédéric Robin; Antony Cougnoux; Lucie Gibold; Richard Bonnet
Journal:  Antimicrob Agents Chemother       Date:  2011-09-19       Impact factor: 5.191

2.  Crystal structures of penicillin-binding protein 6 from Escherichia coli.

Authors:  Yu Chen; Weilie Zhang; Qicun Shi; Dusan Hesek; Mijoon Lee; Shahriar Mobashery; Brian K Shoichet
Journal:  J Am Chem Soc       Date:  2009-10-14       Impact factor: 15.419

3.  Neutron and X-ray crystal structures of a perdeuterated enzyme inhibitor complex reveal the catalytic proton network of the Toho-1 β-lactamase for the acylation reaction.

Authors:  Stephen J Tomanicek; Robert F Standaert; Kevin L Weiss; Andreas Ostermann; Tobias E Schrader; Joseph D Ng; Leighton Coates
Journal:  J Biol Chem       Date:  2012-12-18       Impact factor: 5.157

Review 4.  Fragment-based inhibitor discovery against β-lactamase.

Authors:  Derek A Nichols; Adam R Renslo; Yu Chen
Journal:  Future Med Chem       Date:  2014-03       Impact factor: 3.808

5.  Excess positional mutual information predicts both local and allosteric mutations affecting beta lactamase drug resistance.

Authors:  George A Cortina; Peter M Kasson
Journal:  Bioinformatics       Date:  2016-07-27       Impact factor: 6.937

6.  Antibacterial properties and atomic resolution X-ray complex crystal structure of a ruthenocene conjugated β-lactam antibiotic.

Authors:  Eric M Lewandowski; Joanna Skiba; Nicholas J Torelli; Aleksandra Rajnisz; Jolanta Solecka; Konrad Kowalski; Yu Chen
Journal:  Chem Commun (Camb)       Date:  2015-04-11       Impact factor: 6.222

7.  Antagonism between substitutions in β-lactamase explains a path not taken in the evolution of bacterial drug resistance.

Authors:  Cameron A Brown; Liya Hu; Zhizeng Sun; Meha P Patel; Sukrit Singh; Justin R Porter; Banumathi Sankaran; B V Venkataram Prasad; Gregory R Bowman; Timothy Palzkill
Journal:  J Biol Chem       Date:  2020-04-16       Impact factor: 5.157

8.  Probing the role of the conserved residue Glu166 in a class A β-lactamase using neutron and X-ray protein crystallography.

Authors:  Patricia S Langan; Brendan Sullivan; Kevin L Weiss; Leighton Coates
Journal:  Acta Crystallogr D Struct Biol       Date:  2020-01-24       Impact factor: 7.652

9.  Exploring the inhibition of CTX-M-9 by beta-lactamase inhibitors and carbapenems.

Authors:  Christopher R Bethel; Magdalena Taracila; Teresa Shyr; Jodi M Thomson; Anne M Distler; Kristine M Hujer; Andrea M Hujer; Andrea Endimiani; Krisztina Papp-Wallace; Richard Bonnet; Robert A Bonomo
Journal:  Antimicrob Agents Chemother       Date:  2011-05-09       Impact factor: 5.191

Review 10.  Three decades of the class A beta-lactamase acyl-enzyme.

Authors:  Jed F Fisher; Shahriar Mobashery
Journal:  Curr Protein Pept Sci       Date:  2009-10       Impact factor: 3.272
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