Literature DB >> 17397962

Long-term survival of a patient with small cell lung cancer associated with cancer-associated retinopathy.

Makoto Kobayashi1, Takayuki Ikezoe, Yoshiki Uemura, Hisayuki Ueno, Hirokuni Taguchi.   

Abstract

Cancer-associated retinopathy (CAR) is a rare paraneoplastic disorder that is frequently found in patients with small cell lung cancer (SCLC); it is caused by autoantibody to the 23-kDa photoreceptor protein, recoverin. We report a 9-year survivor of SCLC after concurrent chemoradiotherapy. His anti-recoverin antibody remains positive. Long-term survival without SCLC recurrence might be related to an autoimmunity mechanism that causes CAR due to the presence of anti-recoverin antibody cross-reacting with retinal cells and tumor cells. The current literature review was conducted to evaluate the impact on overall survival according to anti-recoverin antibody status.

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Year:  2007        PMID： 17397962     DOI： 10.1016/j.lungcan.2007.02.015

Source DB:  PubMed          Journal:  Lung Cancer        ISSN： 0169-5002            Impact factor:   5.705


  7 in total

1.  Isoaspartylation appears to trigger small cell lung cancer-associated autoimmunity against neuronal protein ELAVL4.

Authors:  Mario A Pulido; Meleeneh Kazarian DerHartunian; Zhenxia Qin; Eric M Chung; Diane S Kang; Andrew W Woodham; Jeffrey A Tsou; Rinse Klooster; Omid Akbari; Lina Wang; W Martin Kast; Stephen V Liu; Jan J G M Verschuuren; Dana W Aswad; Ite A Laird-Offringa
Journal:  J Neuroimmunol       Date:  2016-09-03       Impact factor: 3.478

2.  Choroidal metastasis in a patient with small cell lung cancer discovered during treatment with chemotherapy.

Authors:  Yusuke Okuma; Yukio Hosomi; Kazuhiro Kitamura; Mari Iguchi; Tatsuru Okamura; Shin Fukami; Tsunekazu Hishima; Masahiko Shibuya
Journal:  Int J Clin Oncol       Date:  2009-12-05       Impact factor: 3.402

3.  Molecular biomarkers for autoimmune retinopathies: significance of anti-transducin-alpha autoantibodies.

Authors:  Grazyna Adamus; Lori Brown; Richard G Weleber
Journal:  Exp Mol Pathol       Date:  2009-09-08       Impact factor: 3.362

Review 4.  Autoantibody targets and their cancer relationship in the pathogenicity of paraneoplastic retinopathy.

Authors:  Grazyna Adamus
Journal:  Autoimmun Rev       Date:  2009-01-23       Impact factor: 9.754

5.  An Exceptionally Favorable Response to Etoposide and Cisplatin.

Authors:  Gautam Valecha; Adarsh Vennepureddy; Uroosa Ibrahim; Marcel Odaimi
Journal:  Cureus       Date:  2015-12-18

Review 6.  What Are the Biomarkers for Immunotherapy in SCLC?

Authors:  Vito Longo; Annamaria Catino; Michele Montrone; Pamela Pizzutilo; Tiziana Annese; Francesco Pesola; Ilaria Marech; Sandro Cassiano; Domenico Ribatti; Domenico Galetta
Journal:  Int J Mol Sci       Date:  2021-10-15       Impact factor: 5.923

7.  An immune-related lncRNA signature predicts prognosis and adjuvant chemotherapeutic response in patients with small-cell lung cancer.

Authors:  Zhihui Zhang; Yuejun Luo; Chaoqi Zhang; Peng Wu; Guochao Zhang; Qingpeg Zeng; Lide Wang; Liyan Xue; Zhaoyang Yang; Hua Zeng; Bo Zheng; Fengwei Tan; Qi Xue; Shugeng Gao; Nan Sun; Jie He
Journal:  Cancer Cell Int       Date:  2021-12-20       Impact factor: 5.722
  7 in total

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