Literature DB >> 17397121

A small molecule targeting the multifactorial nature of Alzheimer's disease.

Andrea Cavalli1, Maria Laura Bolognesi, Simona Capsoni, Vincenza Andrisano, Manuela Bartolini, Elisa Margotti, Antonino Cattaneo, Maurizio Recanatini, Carlo Melchiorre.   

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Year:  2007        PMID： 17397121     DOI： 10.1002/anie.200700256

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  23 in total

Review 1.  Alzheimer's disease and age-related memory decline (preclinical).

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Review 2.  Multi-target design strategies in the context of Alzheimer's disease: acetylcholinesterase inhibition and NMDA receptor antagonism as the driving forces.

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3.  A Fluorescent Styrylquinoline with Combined Therapeutic and Diagnostic Activities against Alzheimer's and Prion Diseases.

Authors:  Matteo Staderini; Suzana Aulić; Manuela Bartolini; Hoang Ngoc Ai Tran; Víctor González-Ruiz; Daniel I Pérez; Nieves Cabezas; Ana Martínez; M Antonia Martín; Vincenza Andrisano; Giuseppe Legname; J Carlos Menéndez; Maria Laura Bolognesi
Journal:  ACS Med Chem Lett       Date:  2012-12-28       Impact factor: 4.345

4.  Potent inhibitors of hepatitis C core dimerization as new leads for anti-hepatitis C agents.

Authors:  Feng Ni; Smitha Kota; Virginia Takahashi; A Donny Strosberg; John K Snyder
Journal:  Bioorg Med Chem Lett       Date:  2011-04-15       Impact factor: 2.823

5.  Multifunctional cholinesterase and amyloid Beta fibrillization modulators. Synthesis and biological investigation.

Authors:  Stefania Butini; Margherita Brindisi; Simone Brogi; Samuele Maramai; Egeria Guarino; Alessandro Panico; Ashima Saxena; Ved Chauhan; Raffaella Colombo; Laura Verga; Ersilia De Lorenzi; Manuela Bartolini; Vincenza Andrisano; Ettore Novellino; Giuseppe Campiani; Sandra Gemma
Journal:  ACS Med Chem Lett       Date:  2013-10-06       Impact factor: 4.345

6.  Biological activity of sym-triazines with acetylcholine-like substitutions as multitarget modulators of Alzheimer's disease.

Authors:  Anthony J Veloso; Ari M Chow; Devjani Dhar; Derek W F Tang; Hashwin V S Ganesh; Svetlana Mikhaylichenko; Ian R Brown; Kagan Kerman
Journal:  ACS Chem Neurosci       Date:  2013-03-21       Impact factor: 4.418

Review 7.  Hybrids: a new paradigm to treat Alzheimer's disease.

Authors:  Manjinder Singh; Maninder Kaur; Navriti Chadha; Om Silakari
Journal:  Mol Divers       Date:  2015-09-02       Impact factor: 2.943

8.  Diaryl hydrazones as multifunctional inhibitors of amyloid self-assembly.

Authors:  Béla Török; Abha Sood; Seema Bag; Rekha Tulsan; Sanjukta Ghosh; Dmitry Borkin; Arleen R Kennedy; Michelle Melanson; Richard Madden; Weihong Zhou; Harry Levine; Marianna Török
Journal:  Biochemistry       Date:  2013-02-06       Impact factor: 3.162

Review 9.  Neuroprotective effects of multifaceted hybrid agents targeting MAO, cholinesterase, iron and β-amyloid in ageing and Alzheimer's disease.

Authors:  Orly Weinreb; Tamar Amit; Orit Bar-Am; Moussa B H Youdim
Journal:  Br J Pharmacol       Date:  2015-12-01       Impact factor: 8.739

Review 10.  Memoquin: a multi-target-directed ligand as an innovative therapeutic opportunity for Alzheimer's disease.

Authors:  Maria Laura Bolognesi; Andrea Cavalli; Carlo Melchiorre
Journal:  Neurotherapeutics       Date:  2009-01       Impact factor: 7.620
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