| Literature DB >> 1738591 |
E Pizzi1, M Attimonelli, S Liuni, C Frontali, C Saccone.
Abstract
A simple method of sequence comparison, based on a correlation analysis of oligonucleotide frequency distributions, is here shown to be a reliable test of overall sequence similarity. The method does not involve sequence alignment procedures and permits the rapid screening of large amounts of sequence data. It identifies those sequences which deserve more careful analysis of sequence similarity at the level of resolution of the single nucleotide. It uses observed quantities only and does not involve the adoption of any theoretical model.Entities:
Mesh:
Substances:
Year: 1992 PMID: 1738591 PMCID: PMC310336 DOI: 10.1093/nar/20.1.131
Source DB: PubMed Journal: Nucleic Acids Res ISSN: 0305-1048 Impact factor: 16.971