Literature DB >> 17382829

Pelvic organ prolapse.

J Eric Jelovsek1, Christopher Maher, Matthew D Barber.   

Abstract

Pelvic organ prolapse is downward descent of female pelvic organs, including the bladder, uterus or post-hysterectomy vaginal cuff, and the small or large bowel, resulting in protrusion of the vagina, uterus, or both. Prolapse development is multifactorial, with vaginal child birth, advancing age, and increasing body-mass index as the most consistent risk factors. Vaginal delivery, hysterectomy, chronic straining, normal ageing, and abnormalities of connective tissue or connective-tissue repair predispose some women to disruption, stretching, or dysfunction of the levator ani complex, connective-tissue attachments of the vagina, or both, resulting in prolapse. Patients generally present with several complaints, including bladder, bowel, and pelvic symptoms; however, with the exception of vaginal bulging, none is specific to prolapse. Women with symptoms suggestive of prolapse should undergo a pelvic examination and medical history check. Radiographic assessment is usually unnecessary. Many women with pelvic organ prolapse are asymptomatic and do not need treatment. When prolapse is symptomatic, options include observation, pessary use, and surgery. Surgical strategies for prolapse can be categorised broadly by reconstructive and obliterative techniques. Reconstructive procedures can be done by either an abdominal or vaginal approach. Although no effective prevention strategy for prolapse has been identified, considerations include weight loss, reduction of heavy lifting, treatment of constipation, modification or reduction of obstetric risk factors, and pelvic-floor physical therapy.

Entities:  

Mesh:

Year:  2007        PMID: 17382829     DOI: 10.1016/S0140-6736(07)60462-0

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  237 in total

1.  Validation of a global pelvic floor symptom bother questionnaire.

Authors:  Thais V Peterson; Deborah R Karp; Vivian C Aguilar; G Willy Davila
Journal:  Int Urogynecol J       Date:  2010-05-11       Impact factor: 2.894

2.  Quantifying vaginal tissue elasticity under normal and prolapse conditions by tactile imaging.

Authors:  Vladimir Egorov; Heather van Raalte; Vincent Lucente
Journal:  Int Urogynecol J       Date:  2011-11-10       Impact factor: 2.894

3.  Extracellular matrix proteases contribute to progression of pelvic organ prolapse in mice and humans.

Authors:  Madhusudhan Budatha; Shayzreen Roshanravan; Qian Zheng; Cecilia Weislander; Shelby L Chapman; Elaine C Davis; Barry Starcher; R Ann Word; Hiromi Yanagisawa
Journal:  J Clin Invest       Date:  2011-04-25       Impact factor: 14.808

4.  In vivo visualization of the levator ani muscle subdivisions using MR fiber tractography with diffusion tensor imaging.

Authors:  Pascal Rousset; Vincent Delmas; Jean-Noël Buy; Alain Rahmouni; Dominique Vadrot; Jean-François Deux
Journal:  J Anat       Date:  2012-07-04       Impact factor: 2.610

Review 5.  An integrative review and severity classification of complications related to pessary use in the treatment of female pelvic organ prolapse.

Authors:  Marwa Abdulaziz; Lynn Stothers; Darren Lazare; Andrew Macnab
Journal:  Can Urol Assoc J       Date:  2015 May-Jun       Impact factor: 1.862

6.  Is it safe and effective to maintain the vaginal pessary without removing it for 2 consecutive years?

Authors:  Alessio Miceli; Manuel Fernández-Sánchez; Juan Polo-Padillo; José-Luis Dueñas-Díez
Journal:  Int Urogynecol J       Date:  2020-02-15       Impact factor: 2.894

7.  Four-defect repair in women with symptomatic anterior compartment prolapse: a large cohort study.

Authors:  S D Thys; D de Ridder; W Everaerts; S van Bruwaene; J Deprest; J P Roovers
Journal:  Int Urogynecol J       Date:  2014-04-26       Impact factor: 2.894

8.  Pelvic floor muscle weakness: a risk factor for anterior vaginal wall prolapse recurrence.

Authors:  Jeffrey S Schachar; Hemikaa Devakumar; Laura Martin; Sara Farag; Eric A Hurtado; G Willy Davila
Journal:  Int Urogynecol J       Date:  2018-03-19       Impact factor: 2.894

9.  Two-year urinary outcomes of sacrocolpopexy with or without transobturator tape: results of a prolapse-reduction stress test-based approach.

Authors:  Myung Jae Jeon; Ji Young Kim; Yeo Jung Moon; Sang Wook Bai; Eun-Hee Yoo
Journal:  Int Urogynecol J       Date:  2014-05-13       Impact factor: 2.894

10.  Additional treatments, satisfaction, symptoms and quality of life in women 1 year after vaginal and abdominal pelvic organ prolapse repair.

Authors:  Laura N Nguyen; Morgan Gruner; Kim A Killinger; Kenneth M Peters; Judith A Boura; Michelle Jankowski; Larry T Sirls
Journal:  Int Urol Nephrol       Date:  2018-03-16       Impact factor: 2.370

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