OBJECTIVE: We discuss the definition of flat colorectal neoplasms, their clinical importance, CT colonography (CTC) findings, techniques for better visualization on CTC, and diagnostic pitfalls of such lesions. CONCLUSION: Flat lesions appear on CTC as plaque-shaped mucosal elevations with or without a central depression, thickened haustral folds, and nodular mucosal surfaces. The sensitivity and optimal techniques of CTC for the detection of flat lesions have not yet been established. Three-dimensional endoluminal fly-through may be helpful for lesion detection. Fecal tagging helps in the distinction of true flat lesions from feces. I.v. contrast enhancement and the review with intermediate soft-tissue window settings, although not routinely used for CTC, may also help lesion visualization.
OBJECTIVE: We discuss the definition of flat colorectal neoplasms, their clinical importance, CT colonography (CTC) findings, techniques for better visualization on CTC, and diagnostic pitfalls of such lesions. CONCLUSION: Flat lesions appear on CTC as plaque-shaped mucosal elevations with or without a central depression, thickened haustral folds, and nodular mucosal surfaces. The sensitivity and optimal techniques of CTC for the detection of flat lesions have not yet been established. Three-dimensional endoluminal fly-through may be helpful for lesion detection. Fecal tagging helps in the distinction of true flat lesions from feces. I.v. contrast enhancement and the review with intermediate soft-tissue window settings, although not routinely used for CTC, may also help lesion visualization.
Authors: Nichole E M Kaufman; Qianli Meng; Kaitlin E Griffin; Sitanshu S Singh; Achyut Dahal; Zehua Zhou; Frank R Fronczek; J Michael Mathis; Seetharama D Jois; M Graça H Vicente Journal: J Med Chem Date: 2019-03-25 Impact factor: 7.446
Authors: Hongbin Zhu; Zhengrong Liang; Perry J Pickhardt; Matthew A Barish; Jiangsheng You; Yi Fan; Hongbing Lu; Erica J Posniak; Robert J Richards; Harris L Cohen Journal: Med Phys Date: 2010-04 Impact factor: 4.071