Literature DB >> 1737573

The endothelium-dependent relaxation of human middle cerebral artery: effects of activated neutrophils.

S E Akopov1, M R Grigorian, E S Gabrielian.   

Abstract

Neutrophils, activated by 4 beta-phorbol-12 beta-myristate-13 alpha-acetate, decreased acetylcholine-induced relaxation of strips of human middle cerebral artery precontracted with noradrenaline. This effect was prevented by catalase, but not by superoxide dismutase. Nifedipine, propranolol and, less markedly, captopril reduced the decrease in acetylcholine-induced relaxation. Aspirin and dipyridamole did not reduce it.

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Year:  1992        PMID: 1737573     DOI: 10.1007/bf01923601

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  8 in total

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Authors:  H Karaki; G B Weiss
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2.  Evidence for role of hydroxyl radical in complement and neutrophil-dependent tissue injury.

Authors:  P A Ward; G O Till; R Kunkel; C Beauchamp
Journal:  J Clin Invest       Date:  1983-09       Impact factor: 14.808

3.  Attenuation of endothelium-dependent relaxation in aorta from diabetic rats.

Authors:  Y Oyama; H Kawasaki; Y Hattori; M Kanno
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4.  Endothelium-dependent relaxation and experimental atherosclerosis in the rabbit aorta.

Authors:  N Sreeharan; R L Jayakody; M P Senaratne; A B Thomson; C T Kappagoda
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5.  Release and metabolism of arachidonic acid in human neutrophils.

Authors:  C E Walsh; B M Waite; M J Thomas; L R DeChatelet
Journal:  J Biol Chem       Date:  1981-07-25       Impact factor: 5.157

6.  Pulmonary endothelial cell killing by human neutrophils. Possible involvement of hydroxyl radical.

Authors:  J Varani; S E Fligiel; G O Till; R G Kunkel; U S Ryan; P A Ward
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7.  The endothelium-dependent relaxation of rabbit aorta: effects of antioxidants and hydroxylated eicosatetraenoic acids.

Authors:  U Förstermann; B Neufang
Journal:  Br J Pharmacol       Date:  1984-08       Impact factor: 8.739

8.  Role of hydrogen peroxide in neutrophil-mediated destruction of cultured endothelial cells.

Authors:  S J Weiss; J Young; A F LoBuglio; A Slivka; N F Nimeh
Journal:  J Clin Invest       Date:  1981-09       Impact factor: 14.808

  8 in total
  5 in total

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Review 2.  The role of oxidative stress and NADPH oxidase in cerebrovascular disease.

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  5 in total

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