AIM: To study whether H pylori are associated with chronic cholecystitis. METHODS: The subjects were divided into three groups: H pylori-infected cholecystitis group, H pylori-negative cholecystitis group and control group. Pathologic changes of the gallbladder were observed by optic and electronic microscopes and the levels of interleukin-1, 6 and 8 (IL-1, 6 and 8) were detected by radioimmunoassay. RESULTS: Histological evidence of chronic cholecystitis including degeneration, necrosis, inflammatory cell infiltration, were found in the region where H pylori colonized. Levels of IL-1, 6 and 8 in gallbladder mucosa homogenates were significantly higher in H pylori-infected cholecystitis group than those in H pylori-negative cholecystitis group and control group. CONCLUSION: H pylori infection may be related to cholecystitis.
AIM: To study whether H pylori are associated with chronic cholecystitis. METHODS: The subjects were divided into three groups: H pylori-infected cholecystitis group, H pylori-negative cholecystitis group and control group. Pathologic changes of the gallbladder were observed by optic and electronic microscopes and the levels of interleukin-1, 6 and 8 (IL-1, 6 and 8) were detected by radioimmunoassay. RESULTS: Histological evidence of chronic cholecystitis including degeneration, necrosis, inflammatory cell infiltration, were found in the region where H pylori colonized. Levels of IL-1, 6 and 8 in gallbladder mucosa homogenates were significantly higher in H pylori-infected cholecystitis group than those in H pylori-negative cholecystitis group and control group. CONCLUSION:H pylori infection may be related to cholecystitis.
Authors: Reinhard K Straubinger; Andrea Greiter; Sean P McDonough; Alexander Gerold; Eugenio Scanziani; Sabina Soldati; Daiva Dailidiene; Giedrius Dailide; Douglas E Berg; Kenneth W Simpson Journal: Infect Immun Date: 2003-05 Impact factor: 3.441
Authors: Manuel R Amieva; Roger Vogelmann; Antonello Covacci; Lucy S Tompkins; W James Nelson; Stanley Falkow Journal: Science Date: 2003-05-30 Impact factor: 47.728