Literature DB >> 17369560

Fresh osteochondral allografting in the treatment of osteochondritis dissecans of the femoral condyle.

Bryan C Emmerson1, Simon Görtz, Amir A Jamali, Christine Chung, David Amiel, William D Bugbee.   

Abstract

BACKGROUND: The treatment of osteochondritis dissecans in the adult knee can be challenging. As part of our comprehensive treatment program, fresh osteochondral allografts have been used in the surgical management of osteochondritis dissecans of the femoral condyle. HYPOTHESIS: Fresh osteochondral allograft transplantation will provide a successful surgical treatment for osteochondritis dissecans of the femoral condyle. STUDY
DESIGN: Case series; Level of evidence, 4.
METHODS: Sixty-six knees in 64 patients underwent fresh osteochondral allografting for the treatment of osteochondritis dissecans. Each patient was evaluated both preoperatively and postoperatively using an 18-point modified D'Aubigné and Postel scale. Subjective assessment was performed using a patient questionnaire. Radiographs were evaluated preoperatively and postoperatively.
RESULTS: Mean follow-up was 7.7 years (range, 2-22 years). There were 45 men and 19 women with a mean age of 28.6 years (range, 15-54 years). All patients had undergone previous surgery. Forty-one lesions involved the medial femoral condyle, and 25 involved the lateral femoral condyle. All were osteochondritis dissecans type 3 or 4. The mean allograft size was 7.5 cm(2). One knee was lost to follow-up. Of the remaining 65 knees, 47 (72%) were rated good/excellent, 7 (11%) were rated fair, and 1 (2%) was rated poor. Ten patients (15%) underwent reoperation. The mean clinical score improved from 13.0 preoperatively to 16.4 postoperatively (P < .01). Fifty-nine of 64 patients completed questionnaires. Subjective knee function improved from a mean of 3.4 to 8.4 on a 10-point scale (P < .01).
CONCLUSION: With greater than 70% good or excellent results, fresh osteochondral allograft transplantation is a successful surgical treatment for osteochondritis dissecans of the femoral condyle.

Entities:  

Mesh:

Year:  2007        PMID: 17369560     DOI: 10.1177/0363546507299932

Source DB:  PubMed          Journal:  Am J Sports Med        ISSN: 0363-5465            Impact factor:   6.202


  88 in total

Review 1.  Surgical treatment for early osteoarthritis. Part I: cartilage repair procedures.

Authors:  A H Gomoll; G Filardo; L de Girolamo; J Espregueira-Mendes; J Esprequeira-Mendes; M Marcacci; W G Rodkey; J R Steadman; R J Steadman; S Zaffagnini; E Kon
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-11-24       Impact factor: 4.342

Review 2.  Surgical treatment for early osteoarthritis. Part II: allografts and concurrent procedures.

Authors:  A H Gomoll; G Filardo; F K Almqvist; W D Bugbee; M Jelic; J C Monllau; G Puddu; W G Rodkey; P Verdonk; R Verdonk; S Zaffagnini; M Marcacci
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-11-09       Impact factor: 4.342

Review 3.  Osteochondritis Dissecans: Etiology, Pathology, and Imaging with a Special Focus on the Knee Joint.

Authors:  Juergen Bruns; Mathias Werner; Christian Habermann
Journal:  Cartilage       Date:  2017-06-22       Impact factor: 4.634

4.  Good clinical results but moderate osseointegration and defect filling of a cell-free multi-layered nano-composite scaffold for treatment of osteochondral lesions of the knee.

Authors:  Dominic T Mathis; Raphael Kaelin; Helmut Rasch; Markus P Arnold; Michael T Hirschmann
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2017-07-15       Impact factor: 4.342

5.  Material properties of fresh cold-stored allografts for osteochondral defects at 1 year.

Authors:  Anil S Ranawat; Armando F Vidal; Chris T Chen; Jonathan A Zelken; A Simon Turner; Riley J Williams
Journal:  Clin Orthop Relat Res       Date:  2008-06-05       Impact factor: 4.176

6.  Treatment of osteochondritis dissecans of the knee with a biomimetic scaffold. A prospective multicenter study.

Authors:  Marco Delcogliano; Amerigo Menghi; Giacomo Placella; Andrea Speziali; Giuliano Cerulli; Giulia Carimati; Stefano Pasqualotto; Massimo Berruto
Journal:  Joints       Date:  2014-08-01

Review 7.  A review of knowledge in osteochondritis dissecans: 123 years of minimal evolution from König to the ROCK study group.

Authors:  Eric W Edmonds; John Polousky
Journal:  Clin Orthop Relat Res       Date:  2013-04       Impact factor: 4.176

8.  Chondrogenic differentiation of adipose-derived adult stem cells by a porous scaffold derived from native articular cartilage extracellular matrix.

Authors:  Nai-Chen Cheng; Bradley T Estes; Hani A Awad; Farshid Guilak
Journal:  Tissue Eng Part A       Date:  2009-02       Impact factor: 3.845

9.  Osteochondritis Dissecans of the Knee: Short-Term Outcomes of a Hybrid Technique to Restore a Partially Salvageable Progeny Fragment.

Authors:  Heath P Melugin; Vishal S Desai; Bruce A Levy; Yoshinari Tanaka; Shuji Horibe; Norimasa Nakamura; Aaron J Krych
Journal:  Cartilage       Date:  2018-08-24       Impact factor: 4.634

10.  Evaluation of microfracture of traumatic chondral injuries to the knee in professional football and rugby players.

Authors:  Masoud Riyami; Christer Rolf
Journal:  J Orthop Surg Res       Date:  2009-05-07       Impact factor: 2.359

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.