OBJECTIVE: To investigate whether corticotropin-releasing hormone (CRH) and corticotropin (ACTH) plasma concentrations in women diagnosed with preterm labor are of potential clinical value in the assessment of the risk of preterm birth. METHOD: Plasma samples of 79 women diagnosed with preterm labor were used in this study. Samples were divided into three groups based on the week of gestation (24th-28th, 29th-32nd, 33rd-37th). CRH and ACTH values were determined by ELISA. RESULT: Mean maternal peripheral plasma values of CRH and ACTH were significantly higher (p<0.001) in women who were initially diagnosed with preterm labor and finally delivered a preterm birth, compared to women with the same diagnosis but with term birth. CONCLUSION: CRH and ACTH serum levels in women diagnosed with preterm labor could be used as predictors for the timing of parturition.
OBJECTIVE: To investigate whether corticotropin-releasing hormone (CRH) and corticotropin (ACTH) plasma concentrations in women diagnosed with preterm labor are of potential clinical value in the assessment of the risk of preterm birth. METHOD: Plasma samples of 79 women diagnosed with preterm labor were used in this study. Samples were divided into three groups based on the week of gestation (24th-28th, 29th-32nd, 33rd-37th). CRH and ACTH values were determined by ELISA. RESULT: Mean maternal peripheral plasma values of CRH and ACTH were significantly higher (p<0.001) in women who were initially diagnosed with preterm labor and finally delivered a preterm birth, compared to women with the same diagnosis but with term birth. CONCLUSION:CRH and ACTH serum levels in women diagnosed with preterm labor could be used as predictors for the timing of parturition.
Authors: Danielle A Swales; Leah A Grande; Deborah A Wing; Michelle Edelmann; Laura M Glynn; Curt Sandman; Roger Smith; Maria Bowman; Elysia Poggi Davis Journal: J Clin Endocrinol Metab Date: 2019-02-01 Impact factor: 5.958
Authors: R Jeanne Ruiz; Susan Gennaro; Caitlin O'Connor; Alok Dwivedi; Anne Gibeau; Tayra Keshinover; Tia Welsh Journal: Biol Res Nurs Date: 2015-10-27 Impact factor: 2.522
Authors: Emily S Barrett; Matthew Corsetti; Drew Day; Sally W Thurston; Christine T Loftus; Catherine J Karr; Kurunthachalam Kannan; Kaja Z LeWinn; Alicia K Smith; Roger Smith; Frances A Tylavsky; Nicole R Bush; Sheela Sathyanarayana Journal: Environ Int Date: 2022-01-07 Impact factor: 9.621