Literature DB >> 17367106

Outcome of chromosomally abnormal pregnancies in Lebanon: obstetricians' roles during and after prenatal diagnosis.

Lama T Eldahdah1, Kelly E Ormond, Anwar H Nassar, Tayma Khalil, Laila F Zahed.   

Abstract

OBJECTIVES: To better understand obstetrician experiences in Lebanon when disclosing abnormal amniocentesis results.
METHODS: Structured interviews with 38 obstetricians identified as caregivers from the American University of Beirut Medical Center Cytogenetics Laboratory database of patients with abnormal amniocentesis results between 1999 and 2005.
RESULTS: Obstetricians were primarily male, Christian, and with an average of 14 years of experience. They reported doing most pre-amniocentesis counseling, including discussion of risk for common autosomal aneuplodies (95%), and procedure-related risk (95%). Obstetricians reported that 80% of patients at risk for aneuploidy underwent amniocentesis. The study population reported on 143 abnormal test results (124 autosomal abnormalities). When disclosing results, obstetricians reportedly discussed primarily physical and cognitive features of the diagnosis. They varied in levels of directiveness and comfort in providing information. Our records showed that 59% of pregnancies with sex chromosome abnormalities were terminated compared to 90% of those with autosomal aneuploidies; various reasons were proposed by obstetricians.
CONCLUSIONS: This study is among the few to assess prenatal diagnosis practices in the Middle East, with a focus on the role of the obstetrician. Given the influence of culture and social norms on prenatal decision-making, it remains important to understand the various impacts on clinical practice in many nations. (c) 2007 John Wiley & Sons, Ltd.

Entities:  

Mesh:

Year:  2007        PMID: 17367106     DOI: 10.1002/pd.1721

Source DB:  PubMed          Journal:  Prenat Diagn        ISSN: 0197-3851            Impact factor:   3.050


  7 in total

1.  Parental decisions regarding a prenatally detected fetal chromosomal abnormality and the impact of genetic counseling: an analysis of 38 cases with aneuploidy in Southeast Turkey.

Authors:  Mahmut Balkan; Sevgi Kalkanli; Halit Akbas; Ahmet Yalinkaya; M Nail Alp; Turgay Budak
Journal:  J Genet Couns       Date:  2010-01-30       Impact factor: 2.537

2.  Parental decisions following prenatal diagnosis of chromosomal abnormalities: implications for genetic counseling practice in Japan.

Authors:  Nobuhiro Suzumori; Kyoko Kumagai; Shinobu Goto; Akira Nakamura; Mayumi Sugiura-Ogasawara
Journal:  J Genet Couns       Date:  2014-08-02       Impact factor: 2.537

Review 3.  Evolution in health and medicine Sackler colloquium: Consanguinity, human evolution, and complex diseases.

Authors:  A H Bittles; M L Black
Journal:  Proc Natl Acad Sci U S A       Date:  2009-09-23       Impact factor: 11.205

4.  Ethical, social, and cultural issues related to clinical genetic testing and counseling in low- and middle-income countries: a systematic review.

Authors:  Adrina Zhong; Benedict Darren; Bethina Loiseau; Li Qun Betty He; Trillium Chang; Jessica Hill; Helen Dimaras
Journal:  Genet Med       Date:  2018-08-03       Impact factor: 8.822

5.  Knowledge, Attitudes, and Practices of Women Toward Prenatal Genetic Testing.

Authors:  Nour Abdo; Nadia Ibraheem; Nail Obeidat; Ashley Graboski-Bauer; Anwar Batieha; Nada Altamimi; Moawia Khatatbih
Journal:  Epigenet Insights       Date:  2018-12-04

6.  The first Fetal Echocardiography experience for Prenatal diagnosis of Congenital Heart Disease in Lebanon: Successes and challenges.

Authors:  Fatme Charafeddine; Ahmad Hachem; Nadine Kibbi; Mohammad Abutaqa; Fadi Bitar; Ziad Bulbul; Issam El-Rassi; Mariam Arabi
Journal:  J Saudi Heart Assoc       Date:  2019-04-11

7.  Offering prenatal diagnostic tests: European guidelines for clinical practice [corrected].

Authors:  Heather Skirton; Lesley Goldsmith; Leigh Jackson; Celine Lewis; Lyn Chitty
Journal:  Eur J Hum Genet       Date:  2013-09-11       Impact factor: 4.246

  7 in total

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